Collated Gene Ontology terms

Biological process: enzyme regulator activity(2024) ubiquitin protein ligase binding(2018, 2019, 2024) endopeptidase activity(2005, 2007, 2013, 2024) protein-macromolecule adaptor activity(2013, 2024) zinc ion binding(2014) protein kinase C binding(2012, 2024) ubiquitin binding(2010) hydrolase activity(2024) ATP binding(2024)

Molecular function: proteasome-mediated ubiquitin-dependent protein catabolic process2013, 2014, 2015, 2017, 2018, 2020, 2021, 2024 regulation of protein catabolic process2024 protein catabolic process2005, 2006, 2024 ubiquitin-dependent protein catabolic process2005, 2007, 2013, 2021, 2024 proteasome assembly2013, 2024 nematode larval development2007, 2024 innate immune response2013, 2024 hyperosmotic response2007, 2024 retina development in camera-type eye2020 response to salicylic acid2013
reproductive process2007 regulation of cell cycle2007 regulation of DNA-templated transcription2024 proteasomal protein catabolic process2018 determination of adult lifespan2020 Golgi to vacuole transport2021

Cellular component: proteasome regulatory particle, base subcomplex2005, 2006, 2013, 2017, 2024 proteasome complex2003, 2010, 2014, 2018, 2019, 2020, 2024 nucleus2005, 2006, 2009, 2012, 2013, 2017, 2018, 2023, 2024 proteasome storage granule2013, 2017, 2024 proteasome accessory complex2012, 2024 membrane2014, 2024 proteasome regulatory particle2003, 2006, 2007, 2014, 2018, 2024 nuclear periphery2019, 2024 ascospore-type prospore nucleus2019, 2024 cytosol2009, 2015, 2016, 2019, 2024
cytoplasm2012, 2013, 2017, 2018, 2024 nucleoplasm2013, 2016, 2017 lysosome2021, 2024 autophagosome2021, 2024 plasma membrane2012, 2019, 2024 extracellular region2016, 2019 nuclear membrane2012, 2024 mitotic spindle2012, 2024 endoplasmic reticulum2018, 2019 cell cortex2012, 2024 secretory granule lumen2016 plasmodesma2021 mitochondrion2019 fungal biofilm matrix2022 ficolin-1-rich granule lumen2016 extracellular exosome2013 azurophil granule lumen2016

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 4/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»
Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
RPN1_SCHPO
PomBase»
2.1
rpn1 26S proteasome regulatory subunit rpn1 (19S regulatory cap region
of 26S protease subunit 2) (Proteasome non-ATPase subunit mts4)
Schizosaccharomyces pombe
TI:4896 None
 
RPN2_SCHPO
PomBase»
0.5
rpn2 26S proteasome regulatory subunit rpn2 Schizosaccharomyces pombe
TI:4896 None
 
RPN1_YEAST
SGD»
3.9
RPN1 26S proteasome regulatory subunit RPN1 (HMG-CoA reductase
degradation protein 2) (Proteasome non-ATPase subunit 1)
Saccharomyces cerevisiae
TI:4932 None
 
RPN2_YEAST
SGD»
4.5
RPN2 26S proteasome regulatory subunit RPN2 Saccharomyces cerevisiae
TI:4932 None
 
PSMD1_RAT
RGD»
1.0
Psmd1 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit
RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)
Rattus norvegicus
TI:10116 None
 
PSMD2_RAT
RGD»
0.5
Psmd2 26S proteasome non-ATPase regulatory subunit 2 Rattus norvegicus
TI:10116 None
 
J3QN38_MOUSE
Ensembl»
0.0
Gm21972 Predicted gene 21972 Mus musculus
TI:10090 None
     
PSMD1_MOUSE
Ensembl»
0.0
Psmd1 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome
regulatory subunit RPN2) (26S proteasome regulatory subunit S1)
Mus musculus
TI:10090 None
 
PSMD2_MOUSE
Ensembl»
0.0
Psmd2 26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit
RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97)
Mus musculus
TI:10090 None
 
PSMD1_HUMAN
Ensembl»
1.9
PSMD1 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit
RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)
Homo sapiens
TI:9606 None
 
PSMD2_HUMAN
Ensembl»
1.1
PSMD2 26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit
S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
Homo sapiens
TI:9606 None
 
A0A8V0YQY8_CHICK
Ensembl»
0.0
PSMD2 26S proteasome non-ATPase regulatory subunit 2 Gallus gallus
TI:9031 None
   
A0A8V0YSB5_CHICK
Ensembl»
0.0
PSMD1 26S proteasome non-ATPase regulatory subunit 1 Gallus gallus
TI:9031 None
   
PSMD1_CHICK
CTD»
0.5
PSMD1 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome
regulatory subunit RPN2) (26S proteasome regulatory subunit S1)
Gallus gallus
TI:9031 None
 
PSMD1_DROME
FlyBase»
3.1
Rpn2 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome
regulatory complex subunit p110) (26S proteasome regulatory subunit RPN2)
Drosophila melanogaster
TI:7227 None
 
Q9VW54_DROME
FlyBase»
3.9
Rpn1 26S proteasome non-ATPase regulatory subunit 2 Drosophila melanogaster
TI:7227 None
 
PSMD1_DICDI
dictyBase»
1.5
psmD1 26S proteasome non-ATPase regulatory subunit 1 Dictyostelium discoideum
TI:44689 None
 
PSMD2_DICDI
dictyBase»
1.3
psmD2 26S proteasome non-ATPase regulatory subunit 2 Dictyostelium discoideum
TI:44689 None
 
F1QK93_DANRE
ZFIN»
0.5
zgc:55818 26S proteasome non-ATPase regulatory subunit 1 Danio rerio
TI:7955 None
 
Q6PHK7_DANRE
ZFIN»
0.8
zgc:65921 26S proteasome non-ATPase regulatory subunit 2 Danio rerio
TI:7955 None
 
PSMD1_CAEEL
WormBase»
1.3
rpn-2 26S proteasome non-ATPase regulatory subunit
1 (26S proteasome regulatory subunit rpn-2)
Caenorhabditis elegans
TI:6239 None
 
Q9GZH5_CAEEL
WormBase»
2.1
rpn-1 26S proteasome non-ATPase regulatory subunit 2 Caenorhabditis elegans
TI:6239 None
 
PSD1A_ARATH
TAIR»
0.0
RPN2A 26S proteasome non-ATPase regulatory subunit 1 homolog A (26S proteasome
regulatory subunit RPN2a) (AtRPN2a) (26S proteasome regulatory subunit S1 homolog A)
Arabidopsis thaliana
TI:3702 None
 
PSD1B_ARATH
TAIR»
0.9
RPN2B 26S proteasome non-ATPase regulatory subunit 1 homolog B (26S proteasome
regulatory subunit RPN2b) (AtRPN2b) (26S proteasome regulatory subunit S1 homolog B)
Arabidopsis thaliana
TI:3702 None
 
PSD2A_ARATH
TAIR»
4.1
RPN1A 26S proteasome non-ATPase regulatory subunit 2 homolog A (26S proteasome
regulatory subunit RPN1a) (AtRPN1a) (26S proteasome regulatory subunit S2 homolog A)
Arabidopsis thaliana
TI:3702 None
 
PSD2B_ARATH
TAIR»
0.9
RPN1B 26S proteasome non-ATPase regulatory subunit 2 homolog B (26S proteasome
regulatory subunit RPN1b) (AtRPN1b) (26S proteasome regulatory subunit S2 homolog B)
Arabidopsis thaliana
TI:3702 None