Collated Gene Ontology terms

Biological process: peptidyl-prolyl cis-trans isomerase activity(2018, 2021, 2022, 2025) isomerase activity(2025) FK506 binding(2003, 2013, 2021) DNA binding(2025)

Molecular function: protein folding2025 response to fungus2018, 2021 response to endoplasmic reticulum stress2020 cellular response to farnesol2012 cellular response to estrogen stimulus2008 asexual reproduction2021

Cellular component: endoplasmic reticulum2003, 2021, 2022, 2025 endoplasmic reticulum lumen2025 membrane2014, 2018, 2025 endoplasmic reticulum membrane2025 nucleus2018, 2025 cytoplasm2018, 2025 chloroplast2018 secretory vesicle2019 plastid2019 plant-type vacuole2021
fungal-type vacuole2018 endomembrane system2014 cytosol2019 Golgi apparatus2021

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 12/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 1/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 0/8 
Bacteria: 2/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8I5ZVA3_RAT
RGD»
0.5
ENSRNOG00000068459 peptidylprolyl isomerase (EC 5.2.1.8) Rattus norvegicus
TI:10116 None
   
A0A8V0ZIR3_CHICK
Ensembl»
0.0
FKBP11 peptidylprolyl isomerase (EC 5.2.1.8) Gallus gallus
TI:9031 None
   
A9JSW0_DANRE
ZFIN»
0.5
fkbp2 peptidylprolyl isomerase (EC 5.2.1.8) Danio rerio
TI:7955 None
 
B0G119_DICDI
dictyBase»
1.0
DDB_G0295681 peptidylprolyl isomerase (EC 5.2.1.8) Dictyostelium discoideum
TI:44689 None
 
D3ZZR9_RAT
RGD»
0.0
Fkbp2 peptidylprolyl isomerase (EC 5.2.1.8) Rattus norvegicus
TI:10116 None
   
FK151_ARATH
TAIR»
0.5
FKBP15-1 Peptidyl-prolyl cis-trans isomerase FKBP15-1 (PPIase FKBP15-1) (EC 5.2.1.8) (15 kDa FK506-binding protein)
(15 kDa FKBP) (FK506-binding protein 15-1) (AtFKBP15-1) (FK506-binding protein 2-1) (Immunophilin FKBP15-1) (Rotamase)		 Arabidopsis thaliana
TI:3702 None
 
FK152_ARATH
TAIR»
3.7
FKBP15-2 Peptidyl-prolyl cis-trans isomerase FKBP15-2 (PPIase FKBP15-2) (EC 5.2.1.8) (15 kDa FK506-binding protein)
(15 kDa FKBP) (FK506-binding protein 15-2) (AtFKBP15-2) (FK506-binding protein 2-2) (Immunophilin FKBP15-2) (Rotamase)		 Arabidopsis thaliana
TI:3702 None
 
FKB11_HUMAN
Ensembl»
0.5
FKBP11 Peptidyl-prolyl cis-trans isomerase FKBP11 (PPIase FKBP11) (EC 5.2.1.8) (19 kDa
FK506-binding protein) (19 kDa FKBP) (FKBP-19) (FK506-binding protein 11) (FKBP-11) (Rotamase)		 Homo sapiens
TI:9606 None
 
FKB11_MOUSE
Ensembl»
0.5
Fkbp11 Peptidyl-prolyl cis-trans isomerase FKBP11 (PPIase FKBP11) (EC 5.2.1.8) (19 kDa
FK506-binding protein) (19 kDa FKBP) (FKBP-19) (FK506-binding protein 11) (FKBP-11) (Rotamase)		 Mus musculus
TI:10090 None
 
FKBP2_DICDI
dictyBase»
0.5
fkbp2 FK506-binding protein 2 (EC 5.2.1.8)
(Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)		 Dictyostelium discoideum
TI:44689 None
 
FKBP2_HUMAN
Ensembl»
1.4
FKBP2 Peptidyl-prolyl cis-trans isomerase FKBP2 (PPIase FKBP2) (EC 5.2.1.8) (13 kDa FK506-binding
protein) (13 kDa FKBP) (FKBP-13) (FK506-binding protein 2) (FKBP-2) (Immunophilin FKBP13) (Rotamase)		 Homo sapiens
TI:9606 None
 
FKBP2_MOUSE
Ensembl»
0.5
Fkbp2 Peptidyl-prolyl cis-trans isomerase FKBP2 (PPIase FKBP2) (EC 5.2.1.8) (13 kDa FK506-binding
protein) (13 kDa FKBP) (FKBP-13) (FK506-binding protein 2) (FKBP-2) (Immunophilin FKBP13) (Rotamase)		 Mus musculus
TI:10090 None
 
FKBP2_YEAST
SGD»
2.1
FPR2 Peptidyl-prolyl cis-trans isomerase FPR2 (PPIase FPR2) (EC 5.2.1.8) (13-kDa membrane-associated
FK506-binding protein) (FKBP-13) (FK506-binding protein 2) (FKBP proline rotamase 2) (FKBP-15)		 Saccharomyces cerevisiae
TI:4932 None
 
FKBP3_DICDI
dictyBase»
1.3
fkbp3 FK506-binding protein 3 (EC 5.2.1.8)
(Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)		 Dictyostelium discoideum
TI:44689 None
 
Q20107_CAEEL
WormBase»
1.0
fkb-1 peptidylprolyl isomerase (EC 5.2.1.8) Caenorhabditis elegans
TI:6239 None
 
Q7ZZA3_DANRE
ZFIN»
1.3
fkbp11 peptidylprolyl isomerase (EC 5.2.1.8) Danio rerio
TI:7955 None
 
Q9VGK3_DROME
FlyBase»
1.5
Dmel\CG14715 peptidylprolyl isomerase (EC 5.2.1.8) Drosophila melanogaster
TI:7227 None