Collated Gene Ontology terms

Biological process: poly(A)-specific ribonuclease activity(2012, 2013, 2016, 2022, 2023, 2024) nucleic acid binding(2024) exonuclease activity(2024) metal ion binding(2007, 2024) 3'-5'-RNA exonuclease activity(2013, 2019, 2024) RNA binding(2024) RNA exonuclease activity(2013, 2024) transcription corepressor activity(2018, 2024) DNA-binding transcription factor binding(2021, 2024) transferase activity(2024)
hydrolase activity2024 piRNA binding2024 structural constituent of ribosome2024 3'-5' exonuclease activity2011 zinc ion binding2023 ribonuclease III activity2024 poly(A) binding2010 phosphoribosyl-AMP cyclohydrolase activity2024 manganese ion binding2023 mRNA binding2007 chromatin binding2017 RNA nuclease activity2023

Molecular function: nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay2017, 2020 mRNA catabolic process2010, 2013, 2018, 2024 miRNA-mediated gene silencing by mRNA destabilization2024 positive regulation of cell population proliferation2013, 2024 nuclear-transcribed mRNA poly(A) tail shortening2011, 2012, 2013, 2016, 2017, 2019, 2020, 2021, 2024 positive regulation of mRNA catabolic process2014, 2019, 2024 RNA-mediated gene silencing2013, 2023, 2024 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening2013, 2024 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay2013, 2024 negative regulation of cell population proliferation2013, 2024
deadenylation-dependent decapping of nuclear-transcribed mRNA2012, 2022, 2024 positive regulation of viral genome replication2017, 2024 negative regulation of type I interferon-mediated signaling pathway2017, 2024 negative regulation of gene expression2015, 2024 negative regulation of DNA-templated transcription2017, 2024 defense response to virus2017, 2024 regulation of tyrosine phosphorylation of STAT protein2017, 2024 regulation of translation2024 positive regulation of transcription by RNA polymerase II2002, 2024 P-body assembly2012, 2024 positive regulation of transcription elongation by RNA polymerase II2016, 2021, 2024 neuron development2015, 2024 transcription elongation by RNA polymerase II2013, 2021, 2024 translation2024 defense response to bacterium2011 spermatogenesis2024 response to wounding2008 post-transcriptional regulation of gene expression2016 phospholipid homeostasis2014 oogenesis2017 negative regulation of translation2013 histidine biosynthetic process2024 fungal-type cell wall biogenesis2014 filamentous growth of a population of unicellular organisms in response to starvation2014 filamentous growth of a population of unicellular organisms in response to biotic stimulus2014 filamentous growth2014 defense response to insect2013 cellular response to starvation2014 RNA processing2024

Cellular component: CCR4-NOT complex2002, 2013, 2016, 2021, 2022, 2024 P-body2010, 2011, 2012, 2013, 2017, 2024 CCR4-NOT core complex2016, 2017, 2024 nucleus2008, 2009, 2012, 2018, 2024 cytoplasm2009, 2012, 2013, 2016, 2017, 2024 nuclear speck2017, 2024 intracellular non-membrane-bounded organelle2022, 2024 nuclear body2023, 2024 membrane2014, 2024 cytosol2009, 2013, 2015, 2022
ribosome2024 ribonucleoprotein complex2024 nucleoplasm2017 cytoplasmic stress granule2016 mating projection tip2018 P granule2010

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 4/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 5 10 15 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
CNOT7_HUMAN
Ensembl»
17.3
CNOT7 CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4)
(BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a)		 Homo sapiens
TI:9606 None
 
CNOT7_MOUSE
Ensembl»
12.3
Cnot7 CCR4-NOT transcription complex subunit 7
(EC 3.1.13.4) (CCR4-associated factor 1) (CAF-1)		 Mus musculus
TI:10090 None
 
A6JPV7_RAT
RGD»
11.5
Cnot7 poly(A)-specific ribonuclease (EC 3.1.13.4) Rattus norvegicus
TI:10116 None
 
CAF1_SCHPO
PomBase»
8.7
caf1 Poly(A) ribonuclease pop2 (EC
3.1.13.4) (CCR4-associated factor 1)		 Schizosaccharomyces pombe
TI:4896 None
 
CNOT7_DANRE
ZFIN»
6.3
cnot7 CCR4-NOT transcription complex subunit 7
(EC 3.1.13.4) (CCR4-associated factor 1) (CAF-1)		 Danio rerio
TI:7955 None
 
CNOT8_HUMAN
Ensembl»
5.6
CNOT8 CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4)
(CAF1-like protein) (CALIFp) (CAF2) (CCR4-associated factor 8) (Caf1b)		 Homo sapiens
TI:9606 None
 
POP2_YEAST
SGD»
5.6
POP2 Poly(A) ribonuclease POP2 (EC
3.1.13.4) (CCR4-associated factor 1)		 Saccharomyces cerevisiae
TI:4932 None
 
CNOT7_CHICK
Ensembl»
5.5
CNOT7 CCR4-NOT transcription complex subunit 7
(EC 3.1.13.4) (CCR4-associated factor 1) (CAF-1)		 Gallus gallus
TI:9031 None
 
X2JCC3_DROME
FlyBase»
5.0
Pop2 poly(A)-specific ribonuclease (EC 3.1.13.4) Drosophila melanogaster
TI:7227 None
 
CNOT7_CAEEL
WormBase»
4.3
ccf-1 CCR4-NOT transcription complex subunit 7
(EC 3.1.13.4) (CCR4-associated factor 1) (CAF1)		 Caenorhabditis elegans
TI:6239 None
 
CAF1I_ARATH
TAIR»
4.0
CAF1-9 Probable CCR4-associated factor 1
homolog 9 (EC 3.1.13.4)		 Arabidopsis thaliana
TI:3702 None
 
A6HEQ7_RAT
RGD»
3.5
Cnot8 poly(A)-specific ribonuclease (EC 3.1.13.4) Rattus norvegicus
TI:10116 None
 
A8E5K6_DANRE
ZFIN»
2.6
wu:fe49a05 poly(A)-specific ribonuclease (EC 3.1.13.4) Danio rerio
TI:7955 None
 
CAF1K_ARATH
TAIR»
2.4
CAF1-11 Probable CCR4-associated factor 1
homolog 11 (EC 3.1.13.4)		 Arabidopsis thaliana
TI:3702 None
 
CNOT8_MOUSE
Ensembl»
2.0
Cnot8 CCR4-NOT transcription complex subunit 8
(EC 3.1.13.4) (CCR4-associated factor 8)		 Mus musculus
TI:10090 None
 
CAF1F_ARATH
TAIR»
1.0
CAF1-6 Probable CCR4-associated factor 1
homolog 6 (EC 3.1.13.4)		 Arabidopsis thaliana
TI:3702 None
 
Q54NG7_DICDI
dictyBase»
1.0
DDB_G0285269 poly(A)-specific ribonuclease (EC 3.1.13.4) Dictyostelium discoideum
TI:44689 None
 
Q54PZ4_DICDI
dictyBase»
1.0
DDB_G0284217 poly(A)-specific ribonuclease (EC 3.1.13.4) Dictyostelium discoideum
TI:44689 None
 
A0A8I6G3B3_RAT
RGD»
0.0
ENSRNOG00000068058 CCR4-NOT transcription complex subunit 7 Rattus norvegicus
TI:10116 None
   
A0A8V0YLI6_CHICK
Ensembl»
0.0
CNOT8 poly(A)-specific ribonuclease (EC 3.1.13.4) Gallus gallus
TI:9031 None
   
CAF1A_ARATH
TAIR»
0.0
CAF1-1 Probable CCR4-associated factor 1
homolog 1 (EC 3.1.13.4)		 Arabidopsis thaliana
TI:3702 None
 
CAF1B_ARATH
TAIR»
0.0
CAF1-2 Probable CCR4-associated factor 1
homolog 2 (EC 3.1.13.4)		 Arabidopsis thaliana
TI:3702 None
 
CAF1C_ARATH
TAIR»
0.0
CAF1-3 Putative CCR4-associated factor 1
homolog 3 (EC 3.1.13.4)		 Arabidopsis thaliana
TI:3702 None
 
CAF1D_ARATH
TAIR»
0.0
CAF1-4 Putative CCR4-associated factor 1
homolog 4 (EC 3.1.13.4)		 Arabidopsis thaliana
TI:3702 None
 
CAF1E_ARATH
TAIR»
0.0
CAF1-5 Probable CCR4-associated factor 1
homolog 5 (EC 3.1.13.4)		 Arabidopsis thaliana
TI:3702 None
 
CAF1G_ARATH
TAIR»
0.0
CAF1-7 Probable CCR4-associated factor 1
homolog 7 (EC 3.1.13.4)		 Arabidopsis thaliana
TI:3702 None
 
CAF1H_ARATH
TAIR»
0.0
CAF1-8 Putative CCR4-associated factor 1
homolog 8 (EC 3.1.13.4)		 Arabidopsis thaliana
TI:3702 None
 
CAF1J_ARATH
TAIR»
0.0
CAF1-10 Probable CCR4-associated factor 1
homolog 10 (EC 3.1.13.4)		 Arabidopsis thaliana
TI:3702 None