Collated Gene Ontology terms

Biological process: oxysterol binding(2023, 2024)

Molecular function: vacuolar proton-transporting V-type ATPase complex assembly2013, 2018, 2024 lysosomal protein catabolic process2017, 2024 lysosomal lumen acidification2017, 2024 intracellular iron ion homeostasis2017, 2024 cellular response to increased oxygen levels2017, 2024 vacuolar acidification2013, 2024 piecemeal microautophagy of the nucleus2021 autophagy of mitochondrion2021

Cellular component: endoplasmic reticulum2009, 2017, 2018, 2024 membrane2024 endoplasmic reticulum membrane2005, 2013, 2024 endomembrane system2014, 2020, 2024 endoplasmic reticulum-Golgi intermediate compartment membrane2016, 2024 COPI-coated vesicle membrane2016, 2024 vacuolar proton-transporting V-type ATPase complex2017, 2024 lysosome2024 cytoplasmic vesicle2024 Vma12-Vma22 assembly complex2015, 2024
transport vesicle2024 BLOC-1 complex2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 12/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
W1NZS9_AMBTC
EnsemblPlants»
0.0
AMTR_s00002p00221840 ATPase, vacuolar ER assembly factor, Vma12 Amborella trichopoda
TI:13333 None
 
H9GI87_ANOCA
Ensembl»
0.0
TMEM199 Transmembrane protein 199 Anolis carolinensis
TI:28377 None
   
F5HJ10_ANOGA
EnsemblMetazoa»
0.0
11176045 AGAP013136-PA Anopheles gambiae
TI:7165 None
 
Q9LVV4_ARATH
TAIR»
0.0
MNB8.4 At5g52980 (ER-based factor for assembly
of V-ATPase) (Uncharacterized protein At5g52980)		 Arabidopsis thaliana
TI:3702 None
 
Q75DN8_ASHGO
EnsemblFungi»
0.0
AGOS_ABL021C ABL021Cp Ashbya gossypii
TI:33169 None
 
Q4WID4_ASPFU
EnsemblFungi»
0.0
AFUA_2G02240 Endoplasmic reticulum-based factor
for assembly of V-ATPase		 Aspergillus fumigatus
TI:746128 None
 
F4NSV8_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_85567 Uncharacterized protein Batrachochytrium dendrobatidis
TI:109871 None
 
F1MFH0_BOVIN
Ensembl»
0.0
TMEM199 Transmembrane protein 199 Bos taurus
TI:9913 None
   
I1I6G9_BRADI
EnsemblPlants»
0.0
100838611 ATPase, vacuolar ER assembly factor, Vma12 Brachypodium distachyon
TI:15368 None
 
A0A9J7LXD6_BRAFL
CTD»
0.0
LOC118425885 Transmembrane protein 199-like isoform X1 Branchiostoma floridae
TI:7739 None
   
A0A078G4N6_BRANA
EnsemblPlants»
0.0
BnaC09g29040D (rape) hypothetical
protein (BnaC09g29040D protein)		 Brassica napus
TI:3708 None
 
A0A078GPD9_BRANA
EnsemblPlants»
0.0
BnaA02g10570D (rape) hypothetical
protein (BnaA02g10570D protein)		 Brassica napus
TI:3708 None
 
A0A078IKG0_BRANA
EnsemblPlants»
0.0
BnaA10g06370D BnaA10g06370D protein Brassica napus
TI:3708 None
 
M4CFW1_BRACM
EnsemblPlants»
0.0
Endoplasmic reticulum-based factor
for assembly of V-ATPase		 Brassica campestris
TI:3711 None
   
M4FIK8_BRACM
EnsemblPlants»
0.0
BRARA_B01483 ATPase, vacuolar ER assembly factor, Vma12 Brassica campestris
TI:3711 None
 
A8WUH1_CAEBR
WormBase»
0.0
CBG02376 CBG_02376 Protein CBG02376 Caenorhabditis briggsae
TI:6238 None
 
Q19259_CAEEL
WormBase»
0.0
CELE_F09E5.11 F09E5.11 Transmembrane protein 199 Caenorhabditis elegans
TI:6239 None
 
A0A1D8PFF4_CANAL
EnsemblFungi»
0.0
VPH2 Vph2p Candida albicans
TI:5476 None
 
A0A8I3MW30_CANLF
Ensembl»
0.0
TMEM199 Transmembrane protein 199 Canis lupus
TI:9612 None
   
A0A2G3AFL5_CAPAN
EnsemblPlants»
0.0
T459_00882 Uncharacterized protein Capsicum annuum
TI:4072 None
 
A8IIR9_CHLRE
EnsemblPlants»
0.0
CHLRE_10g438750v5 Calcium uniporter protein Chlamydomonas reinhardtii
TI:3055 None
 
H2Y286_CIOIN
Ensembl»
0.0
zf(u1like)-1 Zn-finger (U1-like)-1 Ciona intestinalis
TI:7719 None
 
A0A067DMN7_CITSI
Ensembl»
0.0
CISIN_1g028366mg Uncharacterized protein Citrus sinensis
TI:2711 None
 
Q5KB68_CRYNJ
EnsemblFungi»
0.0
CNI03600 Expressed protein Cryptococcus neoformans
TI:5207 None
 
A0A0A0K7F5_CUCSA
EnsemblPlants»
0.0
Csa_6G003470 ATPase, vacuolar ER assembly factor, Vma12 Cucumis sativus
TI:3659 None
 
A8E5C6_DANRE
ZFIN»
0.0
zgc:109974 Transmembrane protein 199 (Zgc:109974 protein) Danio rerio
TI:7955 None
 
E9HGS5_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_301200 Transmembrane protein 199 Daphnia pulex
TI:6669 None
 
F0ZB50_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_75603 Endoplasmic reticulum-based factor
for assembly of V-ATPase		 Dictyostelium purpureum
TI:5786 None
 
Q54FJ8_DICDI
dictyBase»
0.0
DDB_G0290801 Uncharacterized protein Dictyostelium discoideum
TI:44689 None
 
Q8SXS0_DROME
FlyBase»
0.0
Dmel\CG7071 RE40914p (Uncharacterized protein, isoform A) (Uncharacterized
protein, isoform B) (Uncharacterized protein, isoform C)		 Drosophila melanogaster
TI:7227 None
 
F6W5S3_HORSE
Ensembl»
0.0
TMEM199 Transmembrane protein 199 Equus caballus
TI:9796 None
   
A0A022PVZ5_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a013069mg ATPase, vacuolar ER assembly factor, Vma12 Erythranthe guttata
TI:4155 None
 
A0A2I2UD54_FELCA
Ensembl»
0.0
TMEM199 Transmembrane protein 199 Felis catus
TI:9685 None
 
A0A8V1ANL7_CHICK
Ensembl»
0.0
TMEM199 Transmembrane protein 199 Gallus gallus
TI:9031 None
   
I1LD31_SOYBN
EnsemblPlants»
0.0
100499678 ATPase, vacuolar ER assembly factor, Vma12 Glycine max
TI:3847 None
 
I1NHD8_SOYBN
EnsemblPlants»
0.0
100808257 ATPase, vacuolar ER assembly factor, Vma12 Glycine max
TI:3847 None
 
G3QPJ7_GORGO
Ensembl»
0.0
TMEM199 Transmembrane protein 199 Gorilla gorilla
TI:9593 None
 
A0A1U8KM91_GOSHI
Ensembl»
0.0
LOC107918516 Uncharacterized protein LOC107918516 Gossypium hirsutum
TI:3635 None
   
A0A1U8N387_GOSHI
Ensembl»
0.0
LOC107944255 Uncharacterized protein LOC107944255 Gossypium hirsutum
TI:3635 None
   
A0A1U8PV62_GOSHI
Ensembl»
0.0
LOC107962392 Uncharacterized protein LOC107962392 Gossypium hirsutum
TI:3635 None
   
A0A9K3EJT0_HELAN
EnsemblPlants»
0.0
HanXRQr2_Chr13g0602881 ATPase, vacuolar ER assembly factor, Vma12 Helianthus annuus
TI:4232 None
 
T1FFA1_HELRO
EnsemblMetazoa»
0.0
20207500 Uncharacterized protein Helobdella robusta
TI:6412 None
 
TM199_HUMAN
Ensembl»
3.7
TMEM199 Transmembrane protein 199 Homo sapiens
TI:9606 None
 
A0A8I6WT69_HORVV
EnsemblPlants»
0.0
Uncharacterized protein Hordeum vulgare
TI:4513 None
   
A0A2I4DNV6_JUGRE
EnsemblPlants»
0.0
LOC108982016 Uncharacterized protein LOC108982016 Juglans regia
TI:51240 None
   
A0A1Y1HUM8_KLENI
EnsemblPlants»
0.0
KFL_000830140 Uncharacterized protein Klebsormidium nitens
TI:105231 None
 
W5LXP3_LEPOC
Ensembl»
0.0
Transmembrane protein 199 Lepisosteus oculatus
TI:7918 None
 
G7NGJ0_MACMU
Ensembl»
0.0
TMEM199 Transmembrane protein 199 Macaca mulatta
TI:9544 None
 
A0A2C9WC83_MANES
EnsemblPlants»
0.0
MANES_02G087300 ATPase, vacuolar ER assembly factor, Vma12 Manihot esculenta
TI:3983 None
 
A0A2R6WE58_MARPO
EnsemblPlants»
0.0
MARPO_0102s0011 Endoplasmic reticulum-based factor
for assembly of V-ATPase		 Marchantia polymorpha
TI:3197 None
 
G8A2K5_MEDTR
EnsemblPlants»
0.0
11416307 Endoplasmic reticulum-based factor for assembly of V-ATPase
(Putative ATPase, vacuolar ER assembly factor, Vma12)		 Medicago truncatula
TI:3880 None
 
F6QU23_MONDO
Ensembl»
0.0
TMEM199 Transmembrane protein 199 Monodelphis domestica
TI:13616 None
   
TM199_MOUSE
Ensembl»
2.8
Tmem199 Transmembrane protein 199 Mus musculus
TI:10090 None
 
A0A804KK53_MUSAM
EnsemblPlants»
0.0
GSMUA_234580.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A1U8A3U8_NELNU
EnsemblBacteria»
0.0
LOC104596808 Uncharacterized protein LOC104596808 Nelumbo nucifera
TI:4432 None
 
Q7S566_NEUCR
EnsemblFungi»
0.0
NCU02304 Uncharacterized protein Neurospora crassa
TI:5141 None
 
A0A1S3XA55_TOBAC
EnsemblFungi»
0.0
LOC107762816 Uncharacterized protein LOC107762816 isoform X1 Nicotiana tabacum
TI:4097 None
   
A0A1S3Y178_TOBAC
EnsemblFungi»
0.0
LOC107771079 Uncharacterized protein LOC107771079 isoform X1 Nicotiana tabacum
TI:4097 None
   
F7GA02_ORNAN
Ensembl»
0.0
TMEM199 Transmembrane protein 199 Ornithorhynchus anatinus
TI:9258 None
   
A0A3B3HRN3_ORYLA
Ensembl»
0.0
tmem199 Transmembrane protein 199 Oryzias latipes
TI:8090 None
   
H2QCH1_PANTR
Ensembl»
0.0
TMEM199 Transmembrane protein 199 Pan troglodytes
TI:9598 None
 
A0CR61_PARTE
EnsemblProtists»
0.0
GSPATT00009593001 Chromosome undetermined scaffold_25,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0A2K1J1A7_PHYPA
EnsemblPlants»
0.0
PHYPA_023212 Uncharacterized protein Physcomitrium patens
TI:3218 None
 
H3GTJ0_PHYRM
EnsemblProtists»
0.0
Endoplasmic reticulum transmembrane protein Phytophthora ramorum
TI:164328 None
 
Q8ILK6_PLAF7
EnsemblProtists»
0.0
PF3D7_1425700 Uncharacterized protein Plasmodium falciparum
TI:5833 None
 
B9GZ94_POPTR
EnsemblPlants»
0.0
POPTR_003G093800 ATPase, vacuolar ER assembly factor, Vma12 Populus trichocarpa
TI:3694 None
 
A0A2A6CHC2_PRIPA
EnsemblMetazoa»
0.0
WBGene00276334 Transmembrane protein 199 Pristionchus pacificus
TI:54126 None
 
A0A2A6D1B7_PRIPA
EnsemblMetazoa»
0.0
WBGene00099178 Transmembrane protein 199 Pristionchus pacificus
TI:54126 None
 
M5WVJ8_PRUPE
EnsemblPlants»
0.0
PRUPE_5G032500 ATPase, vacuolar ER assembly factor, Vma12 Prunus persica
TI:3760 None
 
E3JX18_PUCGT
EnsemblFungi»
0.0
PGTG_02054 Uncharacterized protein Puccinia graminis
TI:5297 None
 
TM199_RAT
RGD»
5.0
Tmem199 Transmembrane protein 199 Rattus norvegicus
TI:10116 None
 
B9SNT3_RICCO
EnsemblBacteria»
0.0
RCOM_1278160 ATPase, vacuolar ER assembly factor, Vma12 Ricinus communis
TI:3988 None
 
VPH2_YEAST
SGD»
1.6
VPH2 Vacuolar ATPase assembly integral
membrane protein VPH2 (Protein VMA12)		 Saccharomyces cerevisiae
TI:4932 None
 
T0TAX9_SCHJY
EnsemblFungi»
0.0
SJAG_06514 Endoplasmic reticulum membrane protein Schizosaccharomyces japonicus
TI:4897 None
 
VPH2_SCHPO
PomBase»
0.0
vph2 Vacuolar ATPase assembly
integral membrane protein vph2		 Schizosaccharomyces pombe
TI:4896 None
 
A7F0H1_SCLS1
EnsemblFungi»
0.0
SS1G_11089 Uncharacterized protein Sclerotinia sclerotiorum
TI:5180 None
 
D8RT40_SELML
EnsemblPlants»
0.0
SELMODRAFT_271067 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
D8SQI5_SELML
EnsemblPlants»
0.0
SELMODRAFT_181844 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
K4AFA0_SETIT
EnsemblPlants»
0.0
101766491 Uncharacterized protein Setaria italica
TI:4555 None
 
A0A3Q7HTT8_SOLLC
EnsemblPlants»
0.0
Uncharacterized protein Solanum lycopersicum
TI:4081 None
   
A0A3Q7HTV5_SOLLC
EnsemblPlants»
0.0
Uncharacterized protein Solanum lycopersicum
TI:4081 None
   
K4D1S5_SOLLC
EnsemblPlants»
0.0
Uncharacterized protein Solanum lycopersicum
TI:4081 None
   
M1BH77_SOLTU
EnsemblPlants»
0.0
Uncharacterized protein Solanum tuberosum
TI:4113 None
   
M1CNF7_SOLTU
EnsemblPlants»
0.0
102589737 Uncharacterized protein Solanum tuberosum
TI:4113 None
   
C5WQQ5_SORBI
EnsemblPlants»
0.0
SORBI_3001G285800 Uncharacterized protein Sorghum bicolor
TI:4558 None
 
A0A7M7PBD0_STRPU
EnsemblMetazoa»
0.0
Transmembrane protein 199 Strongylocentrotus purpuratus
TI:7668 None
   
A0A287A088_PIG
Ensembl»
0.0
TMEM199 Transmembrane protein 199 Sus scrofa
TI:9823 None
 
B8BSJ8_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_2008 Uncharacterized protein Thalassiosira pseudonana
TI:35128 None
 
A0A061FJL6_THECC
EnsemblPlants»
0.0
TCM_036278 Vacuolar ER assembly factor,
Vma12, putative isoform 1		 Theobroma cacao
TI:3641 None
 
D6W8A4_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_01745 Biogenesis of lysosome-related organelles
complex 1 subunit 5		 Tribolium castaneum
TI:7070 None
 
B3S804_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_60361 Transmembrane protein 199 Trichoplax adhaerens
TI:10228 None
 
A0A3B5XZN9_WHEAT
EnsemblPlants»
0.0
Uncharacterized protein Triticum aestivum
TI:4565 None
   
A0A3B5YXZ7_WHEAT
EnsemblPlants»
0.0
CFC21_006799 Uncharacterized protein Triticum aestivum
TI:4565 None
 
A0A3B5ZTV0_WHEAT
EnsemblPlants»
0.0
CFC21_011706 Uncharacterized protein Triticum aestivum
TI:4565 None
 
D7TTV3_VITVI
EnsemblPlants»
0.0
VIT_02s0012g01580 ATPase, vacuolar ER assembly factor, Vma12 Vitis vinifera
TI:29760 None
 
F7EDY7_XENTR
Xenbase»
0.0
tmem199 LOC100145125 protein (Transmembrane protein 199) Xenopus tropicalis
TI:8364 None
 
Q3B8B0_XENLA
Xenbase»
0.0
tmem199.L MGC132241 protein (Transmembrane protein 199) Xenopus laevis
TI:8355 None
 
Q6CI73_YARLI
EnsemblFungi»
0.0
YALI0_A01001g YALI0A01001p Yarrowia lipolytica
TI:4952 None
 
B6THX5_MAIZE
EnsemblPlants»
0.0
100276771 Uncharacterized protein Zea mays
TI:4577 None
 
A0A0K9NZ59_ZOSMR
EnsemblPlants»
0.0
ZOSMA_49G00810 Endoplasmic reticulum-based factor
for assembly of V-ATPase		 Zostera marina
TI:29655 None
 
A0A0K9PG09_ZOSMR
EnsemblPlants»
0.0
ZOSMA_252G00150 Uncharacterized protein Zostera marina
TI:29655 None