Collated Gene Ontology terms

Biological process: single-stranded DNA binding(2019, 2020, 2024) peptidase activity(2024) lyase activity(2024) DNA binding(2024) protein-DNA covalent cross-linking activity(2024) DNA-(abasic site) binding(2023, 2024) DNA-(apurinic or apyrimidinic site) endonuclease activity(2019)

Molecular function: protein-DNA covalent cross-linking repair2023, 2024 DNA damage response2019, 2020, 2023, 2024 proteolysis2024 positive regulation of isotype switching2020, 2024 somatic hypermutation of immunoglobulin genes2023, 2024 interstrand cross-link repair2023, 2024 double-strand break repair via alternative nonhomologous end joining2020, 2024 SOS response2024 cellular response to iron ion2017

Cellular component: replication fork2023, 2024 chromosome2024 nucleus2018 cytoplasm2018

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 10/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 1/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 34/39 
Archea: 1/8 
Bacteria: 13/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q8GZ60_ARATH
TAIR»
0.0
At2g26470 At2g26470/T9J22.14 At2g26470 (Embryonic stem cell-specific
5-hydroxymethylcytosine-binding protein) (Uncharacterized protein At2g26470/T9J22.14)		 Arabidopsis thaliana
TI:3702 None
 
Q9VHI3_DROME
FlyBase»
0.0
Dmel\CG11986 Abasic site processing protein HMCES (Embryonic stem cell-specific
5-hydroxymethylcytosine-binding protein) (Peptidase HMCES) (SRAP domain-containing protein 1)		 Drosophila melanogaster
TI:7227 None
 
HMCES_CHICK
Ensembl»
3.5
HMCES Abasic site processing protein HMCES (Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein) (ES
cell-specific 5hmC-binding protein) (Peptidase HMCES) (EC 3.4.-.-) (SRAP domain-containing protein 1)		 Gallus gallus
TI:9031 None
 
HMCES_HUMAN
Ensembl»
6.9
HMCES Abasic site processing protein HMCES (Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein) (ES
cell-specific 5hmC-binding protein) (Peptidase HMCES) (EC 3.4.-.-) (SRAP domain-containing protein 1)		 Homo sapiens
TI:9606 None
 
HMCES_MOUSE
Ensembl»
5.2
Hmces Abasic site processing protein HMCES (Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein) (ES
cell-specific 5hmC-binding protein) (Peptidase HMCES) (EC 3.4.-.-) (SRAP domain-containing protein 1)		 Mus musculus
TI:10090 None
 
HMCES_RAT
RGD»
9.0
Hmces Abasic site processing protein HMCES (Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein) (ES
cell-specific 5hmC-binding protein) (Peptidase HMCES) (EC 3.4.-.-) (SRAP domain-containing protein 1)		 Rattus norvegicus
TI:10116 None
 
YM04_YEAST
SGD»
0.0
YMR114C Abasic site processing
protein YMR114C (EC 3.4.-.-)		 Saccharomyces cerevisiae
TI:4932 None
 
A5PLB0_DANRE
ZFIN»
0.0
im:7137789 Abasic site processing protein HMCES (ES cell-specific 5hmC-binding protein) (EC 3.4.-.-)
(Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein) (Peptidase HMCES) (SRAP domain-containing protein 1)		 Danio rerio
TI:7955 None
 
YEDK_ECOLI
EnsemblBacteria»
2.4
yedK Abasic site processing protein YedK (EC 3.4.-.-) Escherichia coli
TI:562 None