Collated Gene Ontology terms

Biological process: 3-hydroxyisobutyryl-CoA hydrolase activity(2003, 2007, 2010, 2012, 2013, 2020, 2025) hydrolase activity(2025) isomerase activity(2025) catalytic activity(2014, 2025) peptidase activity(2025) lyase activity(2025) structural constituent of ribosome(2018, 2025) peroxidase activity(2025) heme binding(2025)

Molecular function: L-valine catabolic process2010, 2012, 2020, 2024, 2025 branched-chain amino acid catabolic process2025 proteolysis2025 mitochondrial translation2018, 2021, 2024 response to oxidative stress2025 response to cold2009 response to auxin2003 fatty acid beta-oxidation2003 cellular oxidant detoxification2025

Cellular component: mitochondrion2009, 2013, 2014, 2016, 2018, 2021, 2024, 2025 cytosol2010, 2019, 2025 mitochondrial matrix2024, 2025 ribosome2025 ribonucleoprotein complex2025 peroxisome2025 mitochondrial small ribosomal subunit2018, 2021, 2025 extracellular region2019, 2025 cytoplasm2017, 2025 nuclear lumen2017
mitochondrial inner membrane2024 extracellular space2025 ciliary plasm2017 chloroplast2018 plastid2019 kinetoplast2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 40/39 
Archea: 0/8 
Bacteria: 7/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
HIBCH_SCHPO
PomBase»
2.1
snr1 Small ribosomal subunit protein mS47 (3-hydroxyisobutyryl-CoA hydrolase, mitochondrial)
(EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)		 Schizosaccharomyces pombe
TI:4896 None
 
HIBCH_YEAST
SGD»
4.2
EHD3 Small ribosomal subunit protein mS47 (3-hydroxyisobutyryl-CoA hydrolase, mitochondrial)
(EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)		 Saccharomyces cerevisiae
TI:4932 None
 
HIBCH_RAT
RGD»
2.0
Hibch 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4)
(3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)		 Rattus norvegicus
TI:10116 None
 
HIBCH_MOUSE
Ensembl»
2.0
Hibch 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4)
(3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)		 Mus musculus
TI:10090 None
 
HIBCH_HUMAN
Ensembl»
5.2
HIBCH 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4)
(3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)		 Homo sapiens
TI:9606 None
 
A0A8V0YJ40_CHICK
Ensembl»
1.0
HIBCH 3-hydroxyisobutyryl-CoA hydrolase (HIB-CoA hydrolase) (HIBYL-CoA-H)
(EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase)		 Gallus gallus
TI:9031 None
   
HIBCH_CHICK
CTD»
1.0
HIBCH 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4)
(3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)		 Gallus gallus
TI:9031 None
 
Q86BP1_DROME
FlyBase»
2.3
Hibch 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC
3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase)		 Drosophila melanogaster
TI:7227 None
 
HIBCH_DICDI
dictyBase»
1.5
hibch 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4)
(3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)		 Dictyostelium discoideum
TI:44689 None
 
Q54JY1_DICDI
dictyBase»
1.0
DDB_G0287741 Enoyl-CoA hydratase/isomerase
domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q54S41_DICDI
TubercuList»
1.0
DDB_G0282681 Enoyl-CoA hydratase/isomerase
domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q55D79_DICDI
dictyBase»
1.0
DDB_G0269756 Enoyl-CoA hydratase/isomerase
domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q55GM8_DICDI
dictyBase»
1.0
DDB_G0267600 Enoyl-CoA hydratase/isomerase
domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q55GN0_DICDI
dictyBase»
1.0
DDB_G0267598 Enoyl-CoA hydratase/isomerase
domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
HIBCH_DANRE
ZFIN»
1.0
hibch 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4)
(3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)		 Danio rerio
TI:7955 None
 
Q19278_CAEEL
WormBase»
1.0
hach-1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC
3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase)		 Caenorhabditis elegans
TI:6239 None
 
HIBC1_ARATH
TAIR»
6.5
CHY1 3-hydroxyisobutyryl-CoA hydrolase 1 (EC 3.1.2.-)
(EC 3.1.2.4) (CoA-thioester hydrolase CHY1)		 Arabidopsis thaliana
TI:3702 None
 
HIBC2_ARATH
TAIR»
1.0
At2g30650 Probable 3-hydroxyisobutyryl-CoA hydrolase
2 (EC 3.1.2.4)		 Arabidopsis thaliana
TI:3702 None
 
HIBC3_ARATH
TAIR»
1.0
At2g30660 Probable 3-hydroxyisobutyryl-CoA hydrolase
3 (EC 3.1.2.4)		 Arabidopsis thaliana
TI:3702 None
 
HIBC4_ARATH
TAIR»
1.0
At3g60510 3-hydroxyisobutyryl-CoA hydrolase-like protein
1, mitochondrial (EC 3.1.2.-)		 Arabidopsis thaliana
TI:3702 None
 
HIBC5_ARATH
TAIR»
1.0
At4g31810 Small ribosomal subunit protein mS47 (3-hydroxyisobutyryl-CoA
hydrolase-like protein 2, mitochondrial) (EC 3.1.2.-)		 Arabidopsis thaliana
TI:3702 None
 
HIBC6_ARATH
TAIR»
1.0
At4g13360 3-hydroxyisobutyryl-CoA hydrolase-like protein
3, mitochondrial (EC 3.1.2.-)		 Arabidopsis thaliana
TI:3702 None
 
HIBC7_ARATH
TAIR»
1.0
At3g24360 3-hydroxyisobutyryl-CoA hydrolase-like protein
4, mitochondrial (EC 3.1.2.-)		 Arabidopsis thaliana
TI:3702 None
 
HIBC8_ARATH
TAIR»
1.0
At1g06550 3-hydroxyisobutyryl-CoA hydrolase-like protein
5 (EC 3.1.2.-)		 Arabidopsis thaliana
TI:3702 None