Collated Gene Ontology terms

Biological process: protein serine/threonine kinase activity(2024) protein kinase activity(2024) ATP binding(2024) nucleic acid binding(2024) structural constituent of ribosome(2024) mRNA binding(2024) GTP binding(2024)

Molecular function: protein import into mitochondrial matrix2005, 2013, 2017, 2020, 2024 protein transport2024 mitochondrial respiratory chain complex I assembly2013, 2024 mitochondrial cytochrome c oxidase assembly2013, 2024 seedling development2012, 2024 protein phosphorylation2024 intracellular protein transport2014, 2020 translation2021, 2024 protein insertion into mitochondrial inner membrane2020

Cellular component: TIM23 mitochondrial import inner membrane translocase complex2013, 2014, 2017, 2020, 2023, 2024 mitochondrion2009, 2012, 2018, 2024 mitochondrial inner membrane2011, 2013, 2020, 2024 membrane2024 mitochondrial membrane2024 ribosome2024 ribonucleoprotein complex2024 plasma membrane2014 mitochondrial intermembrane space2024 cytosol2019

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
U5D1T1_AMBTC
EnsemblPlants»
0.0
AMTR_s00033p00199300 Mitochondrial import inner
membrane translocase subunit Tim21		 Amborella trichopoda
TI:13333 None
 
G1KC76_ANOCA
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Anolis carolinensis
TI:28377 None
   
Q7PPN0_ANOGA
EnsemblMetazoa»
0.0
1275435 Mitochondrial import inner
membrane translocase subunit Tim21		 Anopheles gambiae
TI:7165 None
 
TIM21_ARATH
TAIR»
0.8
TIM21 Probable mitochondrial import inner membrane translocase
subunit TIM21 (Protein SEGREGATION DISTORTION 3)		 Arabidopsis thaliana
TI:3702 None
 
TIM21_ASHGO
EnsemblFungi»
0.0
TIM21 Mitochondrial import inner
membrane translocase subunit TIM21		 Ashbya gossypii
TI:33169 None
 
TIM21_ASPFU
EnsemblFungi»
0.0
tim21 Mitochondrial import inner
membrane translocase subunit tim21		 Aspergillus fumigatus
TI:746128 None
 
F4P2Q6_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_25138 Mitochondrial import inner
membrane translocase subunit Tim21		 Batrachochytrium dendrobatidis
TI:109871 None
 
F1MRI2_BOVIN
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Bos taurus
TI:9913 None
   
TIM21_BOVIN
CTD»
0.0
TIMM21 Mitochondrial import inner membrane translocase
subunit Tim21 (TIM21-like protein, mitochondrial)		 Bos taurus
TI:9913 None
 
A0A0Q3HI93_BRADI
EnsemblPlants»
0.0
BRADI_1g67861v3 Mitochondrial import inner
membrane translocase subunit Tim21		 Brachypodium distachyon
TI:15368 None
 
I1HNS3_BRADI
EnsemblPlants»
0.0
100842549 Mitochondrial import inner
membrane translocase subunit Tim21		 Brachypodium distachyon
TI:15368 None
 
A0A9J7LCT9_BRAFL
CTD»
0.0
LOC118418626 Mitochondrial import inner
membrane translocase subunit Tim21		 Branchiostoma floridae
TI:7739 None
   
A0A078JG01_BRANA
EnsemblPlants»
0.0
BnaAnng20480D Mitochondrial import inner
membrane translocase subunit Tim21		 Brassica napus
TI:3708 None
 
M4CSA0_BRACM
EnsemblPlants»
0.0
Mitochondrial import inner
membrane translocase subunit Tim21		 Brassica campestris
TI:3711 None
   
M4F895_BRACM
EnsemblPlants»
0.0
Mitochondrial import inner
membrane translocase subunit Tim21		 Brassica campestris
TI:3711 None
   
A8WJK3_CAEBR
WormBase»
0.0
CBG23912 CBG_23912 Mitochondrial import inner
membrane translocase subunit Tim21		 Caenorhabditis briggsae
TI:6238 None
 
Q9TXR7_CAEEL
WormBase»
0.5
CELE_F56B3.11 F56B3.11 Mitochondrial import inner
membrane translocase subunit Tim21		 Caenorhabditis elegans
TI:6239 None
 
TIM21_CANAL
EnsemblFungi»
0.0
TIM21 Mitochondrial import inner
membrane translocase subunit TIM21		 Candida albicans
TI:5476 None
 
A0A8I3MCQ0_CANLF
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Canis lupus
TI:9612 None
   
A0A2G3ADQ8_CAPAN
EnsemblPlants»
0.0
T459_00246 Mitochondrial import inner
membrane translocase subunit Tim21		 Capsicum annuum
TI:4072 None
 
A0A2K3DF96_CHLRE
EnsemblPlants»
0.0
CHLRE_09g405550v5 Mitochondrial import inner
membrane translocase subunit Tim21		 Chlamydomonas reinhardtii
TI:3055 None
 
A0A067HCI2_CITSI
Ensembl»
0.0
CISIN_1g022867mg Mitochondrial import inner
membrane translocase subunit Tim21		 Citrus sinensis
TI:2711 None
 
Q5KL41_CRYNJ
EnsemblFungi»
0.0
CNC00840 Mitochondrial import inner
membrane translocase subunit Tim21		 Cryptococcus neoformans
TI:5207 None
 
A0A0A0K9E8_CUCSA
EnsemblPlants»
0.0
Csa_6G046410 Mitochondrial import inner
membrane translocase subunit Tim21		 Cucumis sativus
TI:3659 None
 
E7F4T6_DANRE
ZFIN»
0.5
si:dkey-118j18.1 Mitochondrial import inner
membrane translocase subunit Tim21		 Danio rerio
TI:7955 None
 
E9G2U8_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_97889 Mitochondrial import inner
membrane translocase subunit Tim21		 Daphnia pulex
TI:6669 None
 
Q9VMR0_DROME
FlyBase»
1.0
Dmel\CG7382 Mitochondrial import inner
membrane translocase subunit Tim21		 Drosophila melanogaster
TI:7227 None
 
C8V311_EMENI
EnsemblFungi»
0.0
ANIA_06034 Mitochondrial import inner
membrane translocase subunit Tim21		 Emericella nidulans
TI:162425 None
 
F6XI41_HORSE
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Equus caballus
TI:9796 None
   
A0A022PWB9_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a019727mg Mitochondrial import inner
membrane translocase subunit Tim21		 Erythranthe guttata
TI:4155 None
 
A0A022RTU2_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a011656mg Mitochondrial import inner
membrane translocase subunit Tim21		 Erythranthe guttata
TI:4155 None
 
M3X2F7_FELCA
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Felis catus
TI:9685 None
 
A0A8V0X1C0_CHICK
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Gallus gallus
TI:9031 None
   
A0A0R0IYS7_SOYBN
EnsemblPlants»
0.0
GLYMA_08G276700 Mitochondrial import inner
membrane translocase subunit Tim21		 Glycine max
TI:3847 None
 
C6TAF0_SOYBN
EnsemblPlants»
0.0
100779212 Mitochondrial import inner
membrane translocase subunit Tim21		 Glycine max
TI:3847 None
 
I1LC01_SOYBN
EnsemblPlants»
0.0
100815534 Mitochondrial import inner
membrane translocase subunit Tim21		 Glycine max
TI:3847 None
 
G3RIN9_GORGO
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Gorilla gorilla
TI:9593 None
 
A0A1U8IDF4_GOSHI
Ensembl»
0.0
LOC107895436 Mitochondrial import inner
membrane translocase subunit Tim21		 Gossypium hirsutum
TI:3635 None
   
A0A1U8KFX3_GOSHI
Ensembl»
0.0
LOC107915027 Mitochondrial import inner
membrane translocase subunit Tim21		 Gossypium hirsutum
TI:3635 None
   
A0A251SWU7_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr13g0422791 Mitochondrial import inner
membrane translocase subunit Tim21		 Helianthus annuus
TI:4232 None
 
A0A251TDS3_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr11g0351331 HanXRQr2_Chr11g0516431 Mitochondrial import inner
membrane translocase subunit Tim21		 Helianthus annuus
TI:4232 None
 
A0A9K3HEC0_HELAN
EnsemblPlants»
0.0
HanXRQr2_Chr13g0613521 Mitochondrial import inner
membrane translocase subunit Tim21		 Helianthus annuus
TI:4232 None
 
A0A9K3NXZ1_HELAN
EnsemblPlants»
0.0
HanXRQr2_Chr03g0137471 Mitochondrial import inner
membrane translocase subunit Tim21		 Helianthus annuus
TI:4232 None
 
T1FRF6_HELRO
EnsemblMetazoa»
0.0
20211403 Mitochondrial import inner
membrane translocase subunit Tim21		 Helobdella robusta
TI:6412 None
 
TIM21_HUMAN
Ensembl»
3.5
TIMM21 Mitochondrial import inner membrane translocase
subunit Tim21 (TIM21-like protein, mitochondrial)		 Homo sapiens
TI:9606 None
 
F2E7H0_HORVV
EnsemblPlants»
0.0
Mitochondrial import inner
membrane translocase subunit Tim21		 Hordeum vulgare
TI:4513 None
 
F2EFS1_HORVV
EnsemblPlants»
0.0
Mitochondrial import inner
membrane translocase subunit Tim21		 Hordeum vulgare
TI:4513 None
 
B7PMF6_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW006264 Mitochondrial import inner
membrane translocase subunit Tim21		 Ixodes scapularis
TI:6945 None
 
A0A2I4H1E4_JUGRE
EnsemblPlants»
0.0
LOC109012668 Ribosomal protein L15 Juglans regia
TI:51240 None
   
A0A1Y1IC10_KLENI
EnsemblPlants»
0.0
KFL_003010070 Mitochondrial import inner
membrane translocase subunit Tim21		 Klebsormidium nitens
TI:105231 None
 
W5N828_LEPOC
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Lepisosteus oculatus
TI:7918 None
 
F7FB39_MACMU
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Macaca mulatta
TI:9544 None
 
A0A2C9VTK4_MANES
EnsemblPlants»
0.0
MANES_05G052500 Mitochondrial import inner
membrane translocase subunit Tim21		 Manihot esculenta
TI:3983 None
 
A0A2R6W338_MARPO
EnsemblPlants»
0.0
MARPO_0168s0006 Mitochondrial import inner
membrane translocase subunit Tim21		 Marchantia polymorpha
TI:3197 None
 
A0A072VM55_MEDTR
EnsemblPlants»
0.0
25484536 Mitochondrial import inner
membrane translocase subunit Tim21		 Medicago truncatula
TI:3880 None
 
A0A5F8HAD7_MONDO
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Monodelphis domestica
TI:13616 None
   
A9USX2_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_23273 Mitochondrial import inner
membrane translocase subunit Tim21		 Monosiga brevicollis
TI:81824 None
 
TIM21_MOUSE
Ensembl»
1.5
Timm21 Mitochondrial import inner membrane translocase
subunit Tim21 (TIM21-like protein, mitochondrial)		 Mus musculus
TI:10090 None
 
A0A804I9R8_MUSAM
EnsemblPlants»
0.0
GSMUA_211160.1 Mitochondrial import inner
membrane translocase subunit Tim21		 Musa acuminata
TI:4641 None
 
A0A1U8Q678_NELNU
EnsemblBacteria»
0.0
LOC104598698 Mitochondrial import inner
membrane translocase subunit Tim21		 Nelumbo nucifera
TI:4432 None
   
A7SK73_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g245816 Mitochondrial import inner
membrane translocase subunit Tim21		 Nematostella vectensis
TI:45351 None
 
TIM21_NEUCR
EnsemblFungi»
0.0
tim21 Mitochondrial import inner
membrane translocase subunit tim21		 Neurospora crassa
TI:5141 None
 
A0A1S3YGL2_TOBAC
EnsemblFungi»
0.0
LOC107775889 Mitochondrial import inner
membrane translocase subunit Tim21		 Nicotiana tabacum
TI:4097 None
   
A0A1S4CCZ4_TOBAC
EnsemblFungi»
0.0
LOC107817736 Mitochondrial import inner
membrane translocase subunit Tim21		 Nicotiana tabacum
TI:4097 None
   
F6Y278_ORNAN
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Ornithorhynchus anatinus
TI:9258 None
   
Q10NZ1_ORYSJ
EnsemblPlants»
0.0
LOC_Os03g14890 Os03g0253800 Mitochondrial import inner
membrane translocase subunit Tim21		 Oryza sativa
TI:4530 None
 
H2LUC6_ORYLA
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Oryzias latipes
TI:8090 None
   
H2QEP7_PANTR
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Pan troglodytes
TI:9598 None
 
A0A2K1L1U7_PHYPA
EnsemblPlants»
0.0
PHYPA_002790 Mitochondrial import inner
membrane translocase subunit Tim21		 Physcomitrium patens
TI:3218 None
 
U5FUP0_POPTR
EnsemblPlants»
0.0
POPTR_014G054400 Mitochondrial import inner
membrane translocase subunit Tim21		 Populus trichocarpa
TI:3694 None
 
U5GLE2_POPTR
EnsemblPlants»
0.0
POPTR_002G140700 Mitochondrial import inner
membrane translocase subunit Tim21		 Populus trichocarpa
TI:3694 None
 
A0A2A6CND6_PRIPA
EnsemblMetazoa»
0.0
WBGene00106098 Mitochondrial import inner
membrane translocase subunit Tim21		 Pristionchus pacificus
TI:54126 None
 
M5VXM2_PRUPE
EnsemblPlants»
0.0
PRUPE_8G211200 Mitochondrial import inner
membrane translocase subunit Tim21		 Prunus persica
TI:3760 None
 
E3KVP7_PUCGT
EnsemblFungi»
0.0
PGTG_14471 Mitochondrial import inner membrane translocase subunit TIM21
(Mitochondrial import inner membrane translocase subunit Tim21)		 Puccinia graminis
TI:5297 None
 
TIM21_RAT
RGD»
3.5
Timm21 Mitochondrial import inner membrane translocase
subunit Tim21 (TIM21-like protein, mitochondrial)		 Rattus norvegicus
TI:10116 None
 
B9RD27_RICCO
EnsemblBacteria»
0.0
RCOM_1609100 Mitochondrial import inner
membrane translocase subunit Tim21		 Ricinus communis
TI:3988 None
 
TIM21_YEAST
SGD»
2.5
TIM21 Mitochondrial import inner
membrane translocase subunit TIM21		 Saccharomyces cerevisiae
TI:4932 None
 
B6JXY2_SCHJY
EnsemblFungi»
0.0
SJAG_01442 Mitochondrial import inner
membrane translocase subunit Tim21		 Schizosaccharomyces japonicus
TI:4897 None
 
TIM21_SCHPO
PomBase»
2.5
tim21 Mitochondrial import inner
membrane translocase subunit tim21		 Schizosaccharomyces pombe
TI:4896 None
 
A7FA44_SCLS1
VEuPathDB»
0.0
SS1G_14475 Mitochondrial import inner
membrane translocase subunit Tim21		 Sclerotinia sclerotiorum
TI:5180 None
 
D8S8M6_SELML
EnsemblPlants»
0.0
SELMODRAFT_111521 SELMODRAFT_122297 Mitochondrial import inner
membrane translocase subunit Tim21		 Selaginella moellendorffii
TI:88036 None
 
K4AF31_SETIT
EnsemblPlants»
0.0
Mitochondrial import inner
membrane translocase subunit Tim21		 Setaria italica
TI:4555 None
 
A0A3Q7HTY4_SOLLC
EnsemblPlants»
0.0
101248805 Mitochondrial import inner
membrane translocase subunit Tim21		 Solanum lycopersicum
TI:4081 None
   
M1AWW4_SOLTU
EnsemblPlants»
0.0
Mitochondrial import inner
membrane translocase subunit Tim21		 Solanum tuberosum
TI:4113 None
   
C5WQV6_SORBI
EnsemblPlants»
0.0
SORBI_3001G434200 Mitochondrial import inner
membrane translocase subunit Tim21		 Sorghum bicolor
TI:4558 None
 
A0A7M7HJ52_STRPU
EnsemblMetazoa»
0.0
TIM21-like protein, mitochondrial Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7LVX8_STRPU
EnsemblMetazoa»
0.0
TIM21-like protein, mitochondrial Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7N2W7_STRPU
EnsemblMetazoa»
0.0
TIM21-like protein, mitochondrial Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7N6X9_STRPU
EnsemblMetazoa»
0.0
Mitochondrial import inner
membrane translocase subunit Tim21		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7PQ90_STRPU
EnsemblMetazoa»
0.0
Mitochondrial import inner
membrane translocase subunit Tim21		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7T513_STRPU
EnsemblMetazoa»
0.0
TIM21-like protein, mitochondrial Strongylocentrotus purpuratus
TI:7668 None
   
A0A287BDA0_PIG
Ensembl»
0.0
TIMM21 Mitochondrial import inner
membrane translocase subunit Tim21		 Sus scrofa
TI:9823 None
 
B8C1J4_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_4318 Mitochondrial import inner
membrane translocase subunit Tim21		 Thalassiosira pseudonana
TI:35128 None
 
A0A061DWF5_THECC
EnsemblPlants»
0.0
TCM_005655 Mitochondrial import inner
membrane translocase subunit Tim21		 Theobroma cacao
TI:3641 None
 
D6WL53_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_13506 Mitochondrial import inner
membrane translocase subunit Tim21		 Tribolium castaneum
TI:7070 None
 
B3RVP3_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_55724 Mitochondrial import inner
membrane translocase subunit Tim21		 Trichoplax adhaerens
TI:10228 None
 
A0A3B6AWW9_WHEAT
EnsemblPlants»
0.0
CFC21_016494 Mitochondrial import inner
membrane translocase subunit Tim21		 Triticum aestivum
TI:4565 None
 
A0A3B6C431_WHEAT
EnsemblPlants»
0.0
CFC21_022987 Mitochondrial import inner
membrane translocase subunit Tim21		 Triticum aestivum
TI:4565 None
 
A0A3B6DEA1_WHEAT
EnsemblPlants»
0.0
Mitochondrial import inner
membrane translocase subunit Tim21		 Triticum aestivum
TI:4565 None
   
A0A3B6HPZ4_WHEAT
EnsemblPlants»
0.0
CFC21_051636 Mitochondrial import inner
membrane translocase subunit Tim21		 Triticum aestivum
TI:4565 None
 
A0A3B6IV96_WHEAT
EnsemblPlants»
0.0
CFC21_058186 Mitochondrial import inner
membrane translocase subunit Tim21		 Triticum aestivum
TI:4565 None
 
A0A3B6JJ97_WHEAT
EnsemblPlants»
0.0
CFC21_062262 Mitochondrial import inner
membrane translocase subunit Tim21		 Triticum aestivum
TI:4565 None
 
D7U401_VITVI
EnsemblPlants»
0.0
VIT_02s0033g01350 Mitochondrial import inner
membrane translocase subunit Tim21		 Vitis vinifera
TI:29760 None
 
A0A1L8FSN0_XENLA
Xenbase»
0.0
timm21.S Mitochondrial import inner
membrane translocase subunit Tim21		 Xenopus laevis
TI:8355 None
   
A0A8J1KVY6_XENLA
Xenbase»
0.0
timm21.L Mitochondrial import inner
membrane translocase subunit Tim21		 Xenopus laevis
TI:8355 None
   
Q28HE3_XENTR
Xenbase»
0.0
timm21 Mitochondrial import inner
membrane translocase subunit Tim21		 Xenopus tropicalis
TI:8364 None
 
TIM21_XENLA
Xenbase»
0.0
timm21 Mitochondrial import inner membrane translocase
subunit Tim21 (TIM21-like protein, mitochondrial)		 Xenopus laevis
TI:8355 None
 
TIM21_YARLI
EnsemblFungi»
0.0
TIM21 Mitochondrial import inner
membrane translocase subunit TIM21		 Yarrowia lipolytica
TI:4952 None
 
B4FET7_MAIZE
EnsemblPlants»
0.0
100193378 Mitochondrial import inner
membrane translocase subunit Tim21		 Zea mays
TI:4577 None
 
A0A0K9NH26_ZOSMR
EnsemblPlants»
0.0
ZOSMA_9G00340 Mitochondrial import inner
membrane translocase subunit Tim21		 Zostera marina
TI:29655 None