Collated Gene Ontology terms

Biological process: transcription coregulator activity(2007, 2024) transcription coactivator activity(2006, 2007, 2016, 2018, 2020, 2024) transcription coactivator binding(2021, 2024) DNA binding(2009, 2024) ubiquitin protein ligase activity(2014, 2024) sequence-specific DNA binding(2024) DNA-binding transcription factor activity(2024)

Molecular function: regulation of transcription by RNA polymerase II2005, 2007, 2020, 2023, 2024 positive regulation of DNA-templated transcription2024 positive regulation of transcription by RNA polymerase II2006, 2013, 2024 somatic stem cell population maintenance2012, 2024 positive regulation of transcription initiation by RNA polymerase II2014, 2018, 2023 protein ubiquitination2014, 2024 positive regulation of transcription elongation by RNA polymerase II2014, 2018 RNA polymerase II preinitiation complex assembly2014, 2018 ubiquitin-dependent protein catabolic process2021 proteasome-mediated ubiquitin-dependent protein catabolic process2021
negative regulation of innate immune response2013 defense response to Gram-negative bacterium2013 chromatin remodeling2021

Cellular component: mediator complex2006, 2007, 2009, 2011, 2012, 2020, 2023, 2024 nucleus2005, 2009, 2011, 2014, 2018, 2024 core mediator complex2013, 2014, 2018, 2021, 2024 nucleoplasm2010, 2013, 2018, 2023, 2024 ubiquitin ligase complex2014, 2024 membrane2014, 2024 cytoplasm2010

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 35/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8I6ALZ8_RAT
RGD»
5.1
Med6 Mediator of RNA polymerase II transcription
subunit 6 (Mediator complex subunit 6)		 Rattus norvegicus
TI:10116 None
   
MED6_ARATH
TAIR»
0.0
MED6 Mediator of RNA polymerase
II transcription subunit 6		 Arabidopsis thaliana
TI:3702 None
 
MED6_CAEEL
WormBase»
1.0
mdt-6 Mediator of RNA polymerase II transcription subunit
6 (CeMED6) (Mediator complex subunit 6) (c-MED6) (MED-6)		 Caenorhabditis elegans
TI:6239 None
 
MED6_DANRE
ZFIN»
1.0
med6 Mediator of RNA polymerase II transcription
subunit 6 (Mediator complex subunit 6)		 Danio rerio
TI:7955 None
 
MED6_DICDI
dictyBase»
1.0
med6 Putative mediator of RNA polymerase II transcription
subunit 6 (Putative mediator complex subunit 6)		 Dictyostelium discoideum
TI:44689 None
 
MED6_DROME
FlyBase»
4.7
MED6 Mediator of RNA polymerase II transcription
subunit 6 (Mediator complex subunit 6) (dMED6)		 Drosophila melanogaster
TI:7227 None
 
MED6_HUMAN
Ensembl»
6.1
MED6 Mediator of RNA polymerase II transcription subunit 6 (Activator-recruited cofactor 33
kDa component) (ARC33) (Mediator complex subunit 6) (hMed6) (Renal carcinoma antigen NY-REN-28)		 Homo sapiens
TI:9606 None
 
MED6_MOUSE
Ensembl»
4.4
Med6 Mediator of RNA polymerase II transcription
subunit 6 (Mediator complex subunit 6)		 Mus musculus
TI:10090 None
 
MED6_SCHPO
PomBase»
2.6
med6 Mediator of RNA polymerase II transcription subunit 6 (Mediator
complex subunit 6) (RNA polymerase II mediator complex protein pmc5)		 Schizosaccharomyces pombe
TI:4896 None
 
MED6_YEAST
SGD»
5.8
MED6 Mediator of RNA polymerase II transcription
subunit 6 (Mediator complex subunit 6)		 Saccharomyces cerevisiae
TI:4932 None