Collated Gene Ontology terms

Biological process: small GTPase binding(2016)

Molecular function: endosomal transport2017, 2025 vacuolar transport2024, 2025 regulation of autophagosome maturation2017, 2025 autophagy2025 positive regulation of TORC1 signaling2017, 2025 negative regulation of autophagosome maturation2017, 2025 mitophagy2022, 2025 cellular response to starvation2017, 2025 vesicle-mediated transport2014 regulation of proteasomal ubiquitin-dependent protein catabolic process2022
regulation of mitophagy2024 regulation of autophagy2024 protein destabilization2022 positive regulation of vacuole organization2014 positive regulation of autophagosome maturation2016 negative regulation of proteasomal ubiquitin-dependent protein catabolic process2016 negative regulation of mitophagy2016 flavonoid transport from endoplasmic reticulum to plant-type vacuole2014 endosome to lysosome transport2010 cell fate specification2014 anthocyanin-containing compound biosynthetic process2014

Cellular component: Golgi apparatus2016, 2017, 2022, 2024, 2025 late endosome2016, 2017, 2025 vesicle2017, 2025 cytosol2017, 2025 lysosomal membrane2025 endosome membrane2025 cytoplasm2018, 2025 Golgi membrane2025 membrane2010 late endosome membrane2025
extrinsic component of membrane2014 endolysosome membrane2016 cytoplasmic vesicle2025 autophagosome membrane2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 3/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
U5D418_AMBTC
neXtProt»
0.0
AMTR_s00030p00222710 Uncharacterized protein Amborella trichopoda
TI:13333 None
 
W1PIJ9_AMBTC
euHCVdb»
0.0
AMTR_s00019p00252640 FPL domain-containing protein Amborella trichopoda
TI:13333 None
 
H9G368_ANOCA
Ensembl»
0.0
CLEC16A C-type lectin domain containing 16A Anolis carolinensis
TI:28377 None
   
A0A1S4GG43_ANOGA
EnsemblMetazoa»
0.0
Protein CLEC16A Anopheles gambiae
TI:7165 None
 
TT9_ARATH
TAIR»
5.5
TT9 Protein TRANSPARENT TESTA 9
(Protein GREEN FLUORESCENT SEED 9)		 Arabidopsis thaliana
TI:3702 None
 
F4P975_BATDJ
euHCVdb»
0.0
BATDEDRAFT_35767 FPL domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
A0AAA9T930_BOVIN
Ensembl»
0.0
CLEC16A C-type lectin domain containing 16A Bos taurus
TI:9913 None
   
A0A0Q3H1V0_BRADI
EnsemblPlants»
0.0
LOC100843426 FPL domain-containing protein Brachypodium distachyon
TI:15368 None
 
A0A9J7HTU2_BRAFL
neXtProt»
0.0
LOC118407863 Protein CLEC16A-like Branchiostoma floridae
TI:7739 None
   
A0A078FEQ1_BRANA
neXtProt»
0.0
BnaC07g15730D BnaC07g15730D protein Brassica napus
TI:3708 None
 
A0A078HMP2_BRANA
euHCVdb»
0.0
BnaA07g01380D BnaA07g01380D protein Brassica napus
TI:3708 None
 
M4D6R4_BRACM
EnsemblPlants»
0.0
FPL domain-containing protein Brassica campestris
TI:3711 None
   
M4FCN5_BRACM
EnsemblPlants»
0.0
FPL domain-containing protein Brassica campestris
TI:3711 None
   
A8XZN7_CAEBR
WormBase»
0.0
gop-1 Protein CBR-GOP-1 Caenorhabditis briggsae
TI:6238 None
 
GOP1_CAEEL
WormBase»
1.5
gop-1 Protein CLEC16A homolog Caenorhabditis elegans
TI:6239 None
 
A0A8I3RXC4_CANLF
Ensembl»
0.0
CLEC16A C-type lectin domain containing 16A Canis lupus
TI:9612 None
   
A0A2G2Z1C7_CAPAN
euHCVdb»
0.0
T459_19342 FPL domain-containing protein Capsicum annuum
TI:4072 None
 
A0A2K3D3P1_CHLRE
neXtProt»
0.0
CHLRE_12g515250v5 FPL domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
F6WPI9_CIOIN
Ensembl»
0.0
Uncharacterized protein Ciona intestinalis
TI:7719 None
 
A0A067F3J1_CITSI
euHCVdb»
0.0
CISIN_1g038650mg NECAP PHear domain-containing protein Citrus sinensis
TI:2711 None 		 
 
A0A067FFG9_CITSI
neXtProt»
0.0
CISIN_1g036476mg FPL domain-containing protein Citrus sinensis
TI:2711 None
 
A0A067G501_CITSI
neXtProt»
0.0
CISIN_1g0461932mg Uncharacterized protein Citrus sinensis
TI:2711 None
 
A0A0A0LKC6_CUCSA
neXtProt»
0.0
Csa_2G061590 FPL domain-containing protein Cucumis sativus
TI:3659 None
 
A0A8M2BBF3_DANRE
ZFIN»
1.6
clec16a Protein CLEC16A isoform X1 Danio rerio
TI:7955 None
   
E9GL53_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_304370 Uncharacterized protein Daphnia pulex
TI:6669 None
 
CL16A_DICDI
dictyBase»
1.5
DDB_G0289943 Protein CLEC16A homolog Dictyostelium discoideum
TI:44689 None
 
F0ZMT2_DICPU
TubercuList»
0.0
DICPUDRAFT_15039 Uncharacterized protein Dictyostelium purpureum
TI:5786 None
 
CL16A_DROME
FlyBase»
3.9
ema Protein CLEC16A homolog
(Endosomal maturation defective protein)		 Drosophila melanogaster
TI:7227 None
 
C4LWP9_ENTH1
TubercuList»
0.0
EHI_069620 FPL domain-containing protein Entamoeba histolytica
TI:5759 None
 
A0A5F5PIT6_HORSE
Ensembl»
0.0
CLEC16A C-type lectin domain containing 16A Equus caballus
TI:9796 None
   
A0A022PR33_ERYGU
neXtProt»
0.0
MIMGU_mgv1a001262mg FPL domain-containing protein Erythranthe guttata
TI:4155 None
 
A0ABI7W9D2_FELCA
Ensembl»
0.0
CLEC16A C-type lectin domain containing 16A Felis catus
TI:9685 None
   
A0A8V0ZA80_CHICK
Ensembl»
1.5
CLEC16A C-type lectin domain containing 16A Gallus gallus
TI:9031 None
   
A0A0R0KYG4_SOYBN
EnsemblPlants»
0.0
LOC100815334 Uncharacterized protein Glycine max
TI:3847 None
 
A0A0R0L4J4_SOYBN
EnsemblPlants»
0.0
GLYMA_02G171700 FPL domain-containing protein Glycine max
TI:3847 None
 
I1L1E9_SOYBN
EnsemblPlants»
0.0
LOC100786267 FPL domain-containing protein Glycine max
TI:3847 None 		 
 
I1MH45_SOYBN
EnsemblPlants»
0.0
LOC100789779 FPL domain-containing protein Glycine max
TI:3847 None
 
K7LI04_SOYBN
EnsemblPlants»
0.0
LOC102666080 FPL domain-containing protein Glycine max
TI:3847 None
 
G3RDW4_GORGO
Ensembl»
0.0
CLEC16A C-type lectin domain containing 16A Gorilla gorilla
TI:9593 None
 
A0A1U8HTN4_GOSHI
neXtProt»
0.0
LOC107889433 Protein TRANSPARENT TESTA 9 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A1U8HZE1_GOSHI
euHCVdb»
0.0
LOC107891179 Protein TRANSPARENT TESTA 9 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0ABM2ZHH0_GOSHI
euHCVdb»
0.0
LOC107937193 Protein TRANSPARENT TESTA 9 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0ABM3BEF5_GOSHI
euHCVdb»
0.0
LOC121225267 Protein TRANSPARENT TESTA 9 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A251TSJ1_HELAN
neXtProt»
0.0
HannXRQ_Chr09g0245381 HanXRQr2_Chr09g0372631 FPL domain-containing protein Helianthus annuus
TI:4232 None
 
A0A251V4H3_HELAN
neXtProt»
0.0
HannXRQ_Chr03g0065421 FPL domain-containing protein Helianthus annuus
TI:4232 None
 
A0A251V4J8_HELAN
euHCVdb»
0.0
HannXRQ_Chr03g0065441 HanXRQr2_Chr03g0097181 FPL domain-containing protein Helianthus annuus
TI:4232 None
 
A0A251V5E8_HELAN
euHCVdb»
0.0
HannXRQ_Chr03g0065431 HanXRQr2_Chr03g0097111 Uncharacterized protein Helianthus annuus
TI:4232 None 		 
 
A0A9K3NUQ7_HELAN
euHCVdb»
0.0
HanXRQr2_Chr03g0097101 FPL domain-containing protein Helianthus annuus
TI:4232 None
 
T1FSX3_HELRO
EnsemblMetazoa»
0.0
20211920 Uncharacterized protein Helobdella robusta
TI:6412 None
 
CL16A_HUMAN
Ensembl»
4.7
CLEC16A Protein CLEC16A (C-type lectin
domain family 16 member A)		 Homo sapiens
TI:9606 None
 
A0A8I6XIN8_HORVV
EnsemblPlants»
0.0
LOC123426416 FPL domain-containing protein Hordeum vulgare
TI:4513 None
   
B7QP14_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW015446 Protein CLEC16A, putative Ixodes scapularis
TI:6945 None
 
A0A2I4DFK4_JUGRE
neXtProt»
0.0
LOC108979657 Protein TRANSPARENT TESTA 9 Juglans regia
TI:51240 None
   
A0A2I4H508_JUGRE
euHCVdb»
0.0
LOC109013541 Protein TRANSPARENT TESTA 9-like isoform X1 Juglans regia
TI:51240 None
   
A0A1Y1HWH8_KLENI
euHCVdb»
0.0
KFL_001140010 Uncharacterized protein Klebsormidium nitens
TI:105231 None
 
A0A9R1UWA6_LACSA
euHCVdb»
0.0
LSAT_V11C700364470 FPL domain-containing protein Lactuca sativa
TI:4236 None
 
E9AFT1_LEIMA
TubercuList»
0.0
LMJF_35_4540 FPL domain-containing protein Leishmania major
TI:5664 None
 
W5MG84_LEPOC
Ensembl»
0.0
C-type lectin domain containing 16A Lepisosteus oculatus
TI:7918 None
 
A0A5F8ASC5_MACMU
Ensembl»
0.0
CLEC16A C-type lectin domain containing 16A Macaca mulatta
TI:9544 None
   
A0A2C9VM44_MANES
euHCVdb»
0.0
MANES_06G018200v8 FPL domain-containing protein Manihot esculenta
TI:3983 None
 
A0A2R6XPA9_MARPO
euHCVdb»
0.0
MARPO_0006s0005 Uncharacterized protein Marchantia polymorpha
TI:3197 None
 
A0A072UTY3_MEDTR
EnsemblPlants»
0.0
11445545 FPL domain-containing protein Medicago truncatula
TI:3880 None 		 
 
A0A072V5Z9_MEDTR
EnsemblPlants»
0.0
11445431 FPL domain-containing protein Medicago truncatula
TI:3880 None
 
A0A072VUZ9_MEDTR
EnsemblPlants»
0.0
MTR_1g057130 Uncharacterized protein Medicago truncatula
TI:3880 None
 
A0A5F8G546_MONDO
Ensembl»
0.0
CLEC16A C-type lectin domain containing 16A Monodelphis domestica
TI:13616 None
   
A9UWT0_MONBE
euHCVdb»
0.0
MONBRDRAFT_24555 FPL domain-containing protein Monosiga brevicollis
TI:81824 None
 
CL16A_MOUSE
Ensembl»
7.5
Clec16a Protein CLEC16A Mus musculus
TI:10090 None
 
A0A804J0X6_MUSAM
EnsemblPlants»
0.0
GSMUA_257030.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A1U7Z746_NELNU
euHCVdb»
0.0
LOC104589941 Uncharacterized protein LOC104589941 Nelumbo nucifera
TI:4432 None
   
A0A1U8BJ03_NELNU
euHCVdb»
0.0
LOC104611385 Uncharacterized protein LOC104611385 isoform X1 Nelumbo nucifera
TI:4432 None
   
A7RKV2_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g84933 FPL domain-containing protein Nematostella vectensis
TI:45351 None
 
A7TCC7_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g225185 CLEC16A/TT9 C-terminal domain-containing protein Nematostella vectensis
TI:45351 None 		 
 
A7TCC8_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g154682 FPL domain-containing protein Nematostella vectensis
TI:45351 None
 
F6YL25_ORNAN
Ensembl»
0.0
CLEC16A C-type lectin domain containing 16A Ornithorhynchus anatinus
TI:9258 None
   
A0A0P0W8B1_ORYSJ
euHCVdb»
0.0
Os04g0298600 Os04g0298600 protein Oryza sativa
TI:4530 None
 
H2N2Z9_ORYLA
Ensembl»
0.0
CLEC16A C-type lectin domain containing 16A Oryzias latipes
TI:8090 None
   
H2RAD6_PANTR
Ensembl»
0.0
CLEC16A C-type lectin domain containing 16A Pan troglodytes
TI:9598 None
 
A0BDW0_PARTE
euHCVdb»
0.0
GSPATT00027757001 FPL domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0C2E1_PARTE
euHCVdb»
0.0
GSPATT00034436001 FPL domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0C850_PARTE
euHCVdb»
0.0
GSPATT00036098001 FPL domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0CMJ6_PARTE
euHCVdb»
0.0
GSPATT00008492001 FPL domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0DCU4_PARTE
euHCVdb»
0.0
GSPATT00015720001 FPL domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0DTI0_PARTE
euHCVdb»
0.0
GSPATT00020028001 FPL domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0E1C4_PARTE
euHCVdb»
0.0
GSPATT00022260001 FPL domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0ECA5_PARTE
euHCVdb»
0.0
GSPATT00025659001 FPL domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0EEZ0_PARTE
euHCVdb»
0.0
GSPATT00026204001 FPL domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0A2K1J7U0_PHYPA
EnsemblPlants»
0.0
LOC112293669 Uncharacterized protein Physcomitrium patens
TI:3218 None
 
A0A7I4DYW8_PHYPA
EnsemblPlants»
0.0
LOC112282204 FPL domain-containing protein Physcomitrium patens
TI:3218 None
 
H3GFS7_PHYRM
EnsemblProtists»
0.0
FPL domain-containing protein Phytophthora ramorum
TI:164328 None
 
A0A143ZX45_PLAF7
TubercuList»
0.0
PF3D7_0619000.2 FPL domain-containing protein Plasmodium falciparum
TI:5833 None
 
C6KT30_PLAF7
TubercuList»
0.0
PF3D7_0619000.1 FPL domain-containing protein Plasmodium falciparum
TI:5833 None
 
A0A2K1Y2D2_POPTR
euHCVdb»
0.0
POPTR_013G071700 FPL domain-containing protein Populus trichocarpa
TI:3694 None
 
A0A2K1ZYC8_POPTR
euHCVdb»
0.0
POPTR_006G073600 FPL domain-containing protein Populus trichocarpa
TI:3694 None
 
A0A2K2A5C9_POPTR
euHCVdb»
0.0
POPTR_006G204600 Uncharacterized protein Populus trichocarpa
TI:3694 None
 
B9IN56_POPTR
euHCVdb»
0.0
POPTR_018G140800 FPL domain-containing protein Populus trichocarpa
TI:3694 None
 
A0A2A6CIA2_PRIPA
EnsemblMetazoa»
0.0
WBGene00276438 Gop-1 Pristionchus pacificus
TI:54126 None
   
A0A251N9C6_PRUPE
euHCVdb»
0.0
PRUPE_7G097500 FPL domain-containing protein Prunus persica
TI:3760 None
 
A0A251QTX7_PRUPE
euHCVdb»
0.0
PRUPE_1G073600 FPL domain-containing protein Prunus persica
TI:3760 None 		 
 
A0A8I5ZW58_RAT
RGD»
0.0
Clec16a C-type lectin domain containing 16A Rattus norvegicus
TI:10116 None
   
B9S084_RICCO
euHCVdb»
0.0
RCOM_1300190 FPL domain-containing protein Ricinus communis
TI:3988 None
 
B9T7L6_RICCO
neXtProt»
0.0
RCOM_0308900 Uncharacterized protein Ricinus communis
TI:3988 None
 
D8R072_SELML
euHCVdb»
0.0
SELMODRAFT_405955 FPL domain-containing protein Selaginella moellendorffii
TI:88036 None
 
D8SZR0_SELML
euHCVdb»
0.0
SELMODRAFT_447469 FPL domain-containing protein Selaginella moellendorffii
TI:88036 None
 
K3Y5M8_SETIT
EnsemblPlants»
0.0
FPL domain-containing protein Setaria italica
TI:4555 None
 
K3YA43_SETIT
EnsemblPlants»
0.0
Uncharacterized protein Setaria italica
TI:4555 None 		 
 
A0A3Q7I2N9_SOLLC
EnsemblPlants»
0.0
LOC101267620 FPL domain-containing protein Solanum lycopersicum
TI:4081 None
   
C5Y671_SORBI
neXtProt»
0.0
SORBI_3005G063200 FPL domain-containing protein Sorghum bicolor
TI:4558 None
 
C5YDN1_SORBI
neXtProt»
0.0
SORBI_3006G035300 FPL domain-containing protein Sorghum bicolor
TI:4558 None
 
A0A9R0JKM1_SPIOL
neXtProt»
0.0
LOC110777481 Protein TRANSPARENT TESTA 9 Spinacia oleracea
TI:3562 None
   
A0ABM3QM18_SPIOL
euHCVdb»
0.0
LOC110806025 Protein TRANSPARENT TESTA 9 isoform X1 Spinacia oleracea
TI:3562 None
   
A0A7M7NSW7_STRPU
EnsemblMetazoa»
0.0
Protein CLEC16A Strongylocentrotus purpuratus
TI:7668 None
   
A0A5G2QTZ4_PIG
Ensembl»
0.0
CLEC16A C-type lectin domain containing 16A Sus scrofa
TI:9823 None
   
B8C730_THAPS
neXtProt»
0.0
THAPSDRAFT_7633 FPL domain-containing protein Thalassiosira pseudonana
TI:35128 None
 
B8C8W0_THAPS
euHCVdb»
0.0
THAPSDRAFT_8608 Uncharacterized protein Thalassiosira pseudonana
TI:35128 None
 
B8C8W2_THAPS
euHCVdb»
0.0
THAPSDRAFT_24267 FPL domain-containing protein Thalassiosira pseudonana
TI:35128 None
 
A0A061EUU9_THECC
euHCVdb»
0.0
TCM_022866 Uncharacterized protein isoform 1 Theobroma cacao
TI:3641 None
 
A0A061GRN4_THECC
euHCVdb»
0.0
TCM_039513 Uncharacterized protein isoform 3 Theobroma cacao
TI:3641 None
 
D6WXT8_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_05512 Protein CLEC16A-like Protein Tribolium castaneum
TI:7070 None
 
A2E0Z6_TRIV3
TubercuList»
0.0
TVAG_387690 FPL domain-containing protein Trichomonas vaginalis
TI:5722 None
 
A2E6I5_TRIV3
TubercuList»
0.0
TVAG_487920 FPL domain-containing protein Trichomonas vaginalis
TI:5722 None
 
A2FSX3_TRIV3
TubercuList»
0.0
TVAG_001650 FPL domain-containing protein Trichomonas vaginalis
TI:5722 None
 
B3RQ29_TRIAD
CTD»
0.0
TRIADDRAFT_53756 FPL domain-containing protein Trichoplax adhaerens
TI:10228 None
 
A0A1D5UJ14_WHEAT
EnsemblPlants»
0.0
FPL domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6AYZ2_WHEAT
EnsemblPlants»
0.0
LOC123188935 FPL domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6C8J7_WHEAT
EnsemblPlants»
0.0
LOC123053027 FPL domain-containing protein Triticum aestivum
TI:4565 None 		     
Q38DZ2_TRYB2
TubercuList»
0.0
Tb09.211.1630 FPL domain-containing protein Trypanosoma brucei
TI:5691 None
 
D7SQH3_VITVI
euHCVdb»
0.0
VIT_11s0052g00170 FPL domain-containing protein Vitis vinifera
TI:29760 None
 
F6HKR5_VITVI
neXtProt»
0.0
VIT_08s0007g02410 FPL domain-containing protein Vitis vinifera
TI:29760 None
 
A0A8J0R505_XENTR
Xenbase»
0.0
clec16a Protein CLEC16A isoform X1 Xenopus tropicalis
TI:8364 None
   
A0A8J0TVS6_XENLA
Xenbase»
0.0
clec16a.L Protein CLEC16A isoform X1 Xenopus laevis
TI:8355 None
   
A0A8J0U260_XENLA
Xenbase»
0.0
clec16a.S Protein CLEC16A isoform X1 Xenopus laevis
TI:8355 None
   
K7TNJ4_MAIZE
EnsemblPlants»
0.0
LOC100383777 FPL domain-containing protein Zea mays
TI:4577 None 		 
 
A0A0K9NZT2_ZOSMR
neXtProt»
0.0
ZOSMA_474G00130 FPL domain-containing protein Zostera marina
TI:29655 None