Collated Gene Ontology terms

Biological process: calcium ion binding(2008, 2020, 2023) metal ion binding(2023) calcium ion sensor activity(2019, 2020, 2023) oxidoreductase activity(2023) cadherin binding(2018) 2-alkenal reductase [NAD(P)+] activity(2023)

Molecular function: regulation of cellular hyperosmotic salinity response2019, 2023 neuron projection development2006, 2023 mesoderm development2006

Cellular component: mitochondrial inner membrane2006, 2020, 2023 membrane2023 mitochondrion2009, 2019, 2023 membrane raft2023 plasma membrane2013 muscle tendon junction2013

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
B7PIV6_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW003459 EF-Hand domain-containing protein,
putative (EC 1.3.1.74)		 Ixodes scapularis
TI:6945 None
 
B7Q3Y0_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW021725 EF-hand domain-containing protein Ixodes scapularis
TI:6945 None
 
EFHD1_HUMAN
Ensembl»
2.1
EFHD1 EF-hand domain-containing protein D1
(EF-hand domain-containing protein 1) (Swiprosin-2)		 Homo sapiens
TI:9606 None
 
G3QH56_GORGO
Ensembl»
0.0
EFHD1 EF-hand domain family member D1 Gorilla gorilla
TI:9593 None
 
EFHD1_MOUSE
Ensembl»
3.3
Efhd1 EF-hand domain-containing protein D1 (EF-hand
domain-containing protein 1) (Mitocalcin) (Swiprosin-2)		 Mus musculus
TI:10090 None
 
EFHD2_HUMAN
Ensembl»
1.0
EFHD2 EF-hand domain-containing
protein D2 (Swiprosin-1)		 Homo sapiens
TI:9606 None
 
W5M3D3_LEPOC
Ensembl»
0.0
EF-hand domain-containing protein D2 Lepisosteus oculatus
TI:7918 None
 
K7BEJ8_PANTR
Ensembl»
0.0
EFHD2 EF-hand domain family member D2
(EF-hand domain family, member D2)		 Pan troglodytes
TI:9598 None
 
EFHD2_DROME
FlyBase»
1.3
Swip-1 EF-hand domain-containing protein
D2 homolog (Swiprosin-1 homolog)		 Drosophila melanogaster
TI:7227 None
 
H2QJM2_PANTR
Ensembl»
0.0
EFHD1 EF-hand domain family member D1
(EF-hand domain family, member D1)		 Pan troglodytes
TI:9598 None
 
Q1LVD7_DANRE
ZFIN»
0.5
si:dkey-72l14.9 EF-hand domain family, member D2 (EF-hand
domain-containing protein D2) (Si:dkey-72l14.9) (Si:dkey-72l14.9 protein)		 Danio rerio
TI:7955 None
 
EFHD2_MOUSE
AG»
1.3
Efhd2 EF-hand domain-containing
protein D2 (Swiprosin-1)		 Mus musculus
TI:10090 None
 
G3S780_GORGO
Ensembl»
0.0
EFHD2 EF-hand domain family member D2 Gorilla gorilla
TI:9593 None
 
Q6P3P0_XENTR
Xenbase»
0.0
efhd1 EF-hand domain family member D1 (EF-hand domain family,
member D1) (EF-hand domain-containing protein D1) (Efhd1-prov protein)		 Xenopus tropicalis
TI:8364 None
 
T1FS58_HELRO
EnsemblMetazoa»
0.0
20211655 EF-hand domain-containing protein Helobdella robusta
TI:6412 None
 
A0A2A6B8R3_PRIPA
EnsemblMetazoa»
0.0
WBGene00117789 Efhd-1 Pristionchus pacificus
TI:54126 None
 
A0A337ST01_FELCA
Ensembl»
0.0
EFHD2 EF-hand domain family member D2 Felis catus
TI:9685 None
 
A0A5F5XPW1_FELCA
Ensembl»
0.0
EFHD1 EF-hand domain family member D1 Felis catus
TI:9685 None
 
A7SSA9_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g173776 Uncharacterized protein Nematostella vectensis
TI:45351 None
 
A8XBF2_CAEBR
WormBase»
0.0
CBG10585 CBG_10585 Protein CBG10585 Caenorhabditis briggsae
TI:6238 None
 
A8XNR0_CAEBR
WormBase»
0.0
CBG16285 CBG_16285 Protein CBG16285 Caenorhabditis briggsae
TI:6238 None
 
A8XTV9_CAEBR
WormBase»
0.0
CBG18697 CBG_18697 Protein CBG18697 Caenorhabditis briggsae
TI:6238 None
 
A9UV99_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_18271 EF-hand domain-containing protein Monosiga brevicollis
TI:81824 None
 
B0K066_CAEBR
WormBase»
0.0
efhd-1 Protein CBG02826 Caenorhabditis briggsae
TI:6238 None
 
B3RZU5_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_26114 EF-hand domain-containing protein Trichoplax adhaerens
TI:10228 None
 
D6WXL8_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_05544 EF-hand domain-containing protein
D2 homolog-like Protein		 Tribolium castaneum
TI:7070 None
 
E9HN19_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_231804 EF-hand domain-containing protein Daphnia pulex
TI:6669 None
 
E9I0S8_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_68015 EF-hand domain-containing protein Daphnia pulex
TI:6669 None
 
EFHD1_BOVIN
Ensembl»
0.0
EFHD1 EF-hand domain-containing protein D1
(EF-hand domain-containing protein 1) (Swiprosin-2)		 Bos taurus
TI:9913 None
 
EFHD2_BOVIN
Ensembl»
0.0
EFHD2 EF-hand domain-containing
protein D2 (Swiprosin-1)		 Bos taurus
TI:9913 None
 
EFHD2_RAT
RGD»
1.0
Efhd2 EF-hand domain-containing
protein D2 (Swiprosin-1)		 Rattus norvegicus
TI:10116 None
 
F1R647_DANRE
ZFIN»
0.5
fj19b07 EF-hand domain family, member
D1 (EF-hand domain-containing protein D1)		 Danio rerio
TI:7955 None
 
F6SJE3_CIOIN
Ensembl»
0.0
EF-hand domain-containing protein Ciona intestinalis
TI:7719 None
 
F6UUX9_MACMU
Ensembl»
0.0
EFHD2 EF-hand domain family member
D2 (EF-hand domain-containing protein D2)		 Macaca mulatta
TI:9544 None
 
F7H631_MACMU
Ensembl»
0.0
EFHD1 EF-hand domain family member D1
(EF-hand domain-containing protein D1 isoform 1)		 Macaca mulatta
TI:9544 None
 
H2XSU0_CIOIN
Ensembl»
0.0
LOC100181008 EF-hand domain-containing protein D2-like Ciona intestinalis
TI:7719 None
 
Q5M8L9_XENTR
Xenbase»
0.0
efhd2 EF-hand domain family member D2 (EF-hand domain
family, member D2) (EF-hand domain-containing protein D2)		 Xenopus tropicalis
TI:8364 None
 
Q7PFP7_ANOGA
EnsemblMetazoa»
0.0
1271380 AGAP009528-PA Anopheles gambiae
TI:7165 None
 
Q9U2A6_CAEEL
WormBase»
0.5
efhd-1 EF-hand domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q9VFE1_DROME
FlyBase»
0.5
Dmel\CG14861 EF-hand domain-containing protein Drosophila melanogaster
TI:7227 None
 
W5MS65_LEPOC
Ensembl»
0.0
EF-hand domain family member D1 Lepisosteus oculatus
TI:7918 None
 
A0A3B3I0C5_ORYLA
Ensembl»
0.0
efhd2 EF-hand domain family member D2 Oryzias latipes
TI:8090 None
   
A0A5F8GD38_MONDO
Ensembl»
0.0
EF-hand domain-containing protein Monodelphis domestica
TI:13616 None
   
A0A5F8GGP6_MONDO
Ensembl»
0.0
EF-hand domain-containing protein Monodelphis domestica
TI:13616 None
   
A0A5F8GXE3_MONDO
Ensembl»
0.0
EF-hand domain-containing protein Monodelphis domestica
TI:13616 None
   
A0A5F8HDK6_MONDO
Ensembl»
0.0
EF-hand domain-containing protein Monodelphis domestica
TI:13616 None
   
A0A5F8HDZ8_MONDO
Ensembl»
0.0
EF-hand domain-containing protein Monodelphis domestica
TI:13616 None
   
A0A6I8NWU8_ORNAN
Ensembl»
0.0
EFHD2 EF-hand domain family member D2 Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8P994_ORNAN
Ensembl»
0.0
EFHD1 EF-hand domain family member D1 Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7HGL0_STRPU
EnsemblMetazoa»
0.0
EF-hand domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3PSQ1_CANLF
Ensembl»
0.0
EFHD1 EF-hand domain family member D1 Canis lupus
TI:9612 None
   
A0A8V0ZGC5_CHICK
Ensembl»
0.0
EFHD2 EF-hand domain family member D2 Gallus gallus
TI:9031 None
   
A0A8V0ZRX2_CHICK
Ensembl»
0.0
EFHD1 EF-hand domain family member D1 Gallus gallus
TI:9031 None
   
A0A9J7NAG2_BRAFL
CTD»
0.0
LOC118430384 EF-hand domain-containing protein D2-like Branchiostoma floridae
TI:7739 None
   
D4A9T5_RAT
RGD»
2.0
Efhd1 EF-hand domain family, member D1 Rattus norvegicus
TI:10116 None
   
F1SMT0_PIG
Ensembl»
0.0
EFHD1 EF-hand domain family member D1 Sus scrofa
TI:9823 None
   
F1SUW3_PIG
Ensembl»
0.0
EFHD2 EF-hand domain family member D2 Sus scrofa
TI:9823 None
   
F6QSH6_MONDO
Ensembl»
0.0
EF-hand domain-containing protein Monodelphis domestica
TI:13616 None
   
F7CN52_MONDO
Ensembl»
0.0
EF-hand domain-containing protein Monodelphis domestica
TI:13616 None
   
G1KFE1_ANOCA
Ensembl»
0.0
EFHD1 EF-hand domain family member D1 Anolis carolinensis
TI:28377 None
   
H2MJZ6_ORYLA
Ensembl»
0.0
LOC101163191 EF-hand domain-containing protein D1 Oryzias latipes
TI:8090 None